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Table 1 Baseline clinical characteristics, treatment outcomes and prognosis for patients with PCNSL

From: The role of surgical resection in primary central nervous system lymphoma: a single-center retrospective analysis of 70 patients

Characteristics

Resection(n = 28)

Biopsy(n = 42)

Total(n = 70)

χ2/t

P value

Sex

   

0.972

0.324

 Male

18

22

40

  

 Female

10

20

30

  

Age

47.9 ± 15.9

56.9 ± 12.1

53.3 ± 14.3

2.686

0.995

KPS

84.3 ± 16.7

73.1 ± 13.7

77.6 ± 15.8

−3.068

0.002

IELSG score

   

10.303

0.006

 Low risk(0–1)

16

9

25

  

 Intermediate risk(2–3)

10

22

32

  

 High risk(4–5)

2

11

13

  

Present symptoms

 Headache

15

30

45

2.333

0.127

 Limb weakness

12

22

34

0.610

0.435

 Mental impairment

8

18

26

1.469

0.226

 Aphasia

3

7

10

0.486

0.486

 Ataxia

3

5

8

0.024

0.878

 Seizure

2

3

5

0.000

1.000

 Other

3

2

5

0.897

0.343

Duration of symptoms

4.3 ± 7.2

6.9 ± 13.3

5.8 ± 11.2

0.945

0.826

Numbers of tumors

   

14.593

0.000

 Single

23

15

38

  

 Multiple

5

27

32

  

The maximum diameter of the target

30.2 ± 10.6

29.7 ± 8.7

29.9 ± 9.5

−0.216

0.415

Location

   

22.451

0.000

 Deep location

1

16

17

  

 Infratentorial

3

14

17

  

 Supratentorial

24

12

36

  

Adjuvant therapies

   

1.324

0.516

 Chemotherapy

14

18

32

  

 Radiotherapy

5

5

10

  

 Chemotherapy and radiotherapy

9

19

28

  

Changes in symptoms

   

19.973

0.000

 Aggravation

5

10

15

  

 Improvement

14

2

16

  

 Static

9

30

39

  

Complication

   

0.273

0.601

 No

25

39

64

  

 Yes

3

3

6

  

Overall survival

23.4 ± 13.0

11.2 ± 6.2

16.1 ± 11.2

−5.263

0.000

Progression-free survival

8.6 ± 4.7

4.6 ± 3.2

6.2 ± 4.3

−4.241

0.000