Fig. 4

Case 3. a CT angiography 3D reconstruction demonstrating multiple fusiform aneurysms of the hepatic, splenic, and superior mesenteric arteries (arrows). b H&E staining shows the cross-section of the aneurysm tip (original × 40). c Medium power microscopic images showing inflammation involving the aneurysm wall (original × 100). Immunohistochemical staining with the antibodies against p65 subunit of NFkB (d, original × 100) and TNFa (e, original × 100) shows focal and strong positive staining within the inflammatory infiltrates as expected. f, g 3D reconstruction of vertebrobasilar system after conventional angiography and PED deployment into the left vertebral artery (f), and repeat procedure 3 months later with second PED demonstrating overlapping stents and smaller aneurysm (g). Note reduction of flowing portion of the aneurysm sac as contemporaneously performed MR demonstrated continued enlargement of the thrombosed aneurysm sac with mass effect.