Time course of outcome in poor grade subarachnoid hemorrhage patients: a longitudinal retrospective study

BMC Neurology

Table 2 Cox regression for factors associated with hospital mortality

	Univariable analysis HR (95 % CI)	P value	Multivariable analysis HR (95 % CI)	P value
Age	1.02 (1.01–1.03)	0.002	1.02 (1.00-1.03)	0.022
SOFA score	1.18 (1.12–1.24)	0.001	1.10 (1.03–1.17)	0.006
WFNS 5	2.80 (1.97–3.98)	0.001	2.12 (1.43–3.14)	0.001
Endovascular treatment	0.34 (0.25–0.45)	0.001	0.51 (0.36–0.73)	0.001
Prophylactic nimodipine	0.29 (0.22–0.38)	0.001	0.50 (0.35–0.72)	0.001
Intracranial hypertension	4.80 (3.23–7.12)	0.001	3.56 (2.33–5.41)	0.001
Rebleeding	2.09 (1.35–3.23)	0.001	1.39 (0.86–2.24)	0.174
Hydrocephalus	0.63 (0.47–0.84)	0.001	0.60 (0.43–0.84)	0.002
Seizures	0.60 (0.43–0.84)	0.003	0.84 (0.58–1.20)	0.316
Diabetes mellitus	0.56 (0.32–0.96)	0.035	0.72 (0.41–1.26)	0.254
Heart disease	1.45 (1.01–2.07)	0.045	1.36 (0.90–2.06)	0.151
Intraparenchymal hematoma	1.01 (0.76–1.33)	0.951	0.91 (0.67–1.23)	0.545
2008–2011	0.68 (0.44–1.06)	0.090	0.55 (0.34–0.89)	0.015
2012–2015	1.01 (0.69–1.46)	0.981	0.71 (0.46–1.09)	0.117
2016–2018	0.69 (0.46–1.03)	0.072	0.33 (0.20–0.53)	0.001

Goodness of fit: p = 0.37; WFNS world federation of neurological surgeons; HR hazard ratio; CI confidence interval. Values in bold represent statistical significance in the multivariable analysis

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