Skip to main content

Table 3 Exposure to antiepileptic drugs

From: Risk of ischaemic stroke associated with antiepileptic drugs: a population-based case-control study in Catalonia

N, % Total N = 22,271 Cases N = 2,865 Controls N = 19,406 p-value
Carbamazepine exposure 1238, 5.6 169, 5.9 1069, 5.5 0.407
Current exposure 321, 1.4 52, 1.8 269, 1.4
Past exposure 202, 0.9 32, 1.1 170, 0.9
Monotherapy 140, 0.6 15, 0.5 125, 0.6
Clonazepam 4675, 21.0 570, 19.9 4105, 21.2 0.128
Current 1089, 4.9 135, 4.7 954, 4.9
Past 1019, 4.6 124, 4.3 895, 4.6
Monotherapy 525, 2.4 52, 1.8 473, 2.4
Gabapentin 8861, 39.8 1138, 39.7 7723, 39.8 0.951
Current 1814, 8.1 296, 10.3 1518, 7.8
Past 1994, 9.0 244, 8.5 1750, 9,0
Monotherapy 1060, 4.8 177, 6.2 883, 4.6
Lamotrigine 575, 2.6 94, 3.3 481, 2.5 0.012
Current 191, 0.9 38, 1.3 153, 0.8
Past 146, 0.7 21, 0.7 125, 0.6
Monotherapy 72, 0.3 14, 0.5 58, 0.3
Levetiracetam 654, 2.9 231, 8.1 423, 2.2 <0.001
Current 383, 1.7 166, 5.8 217, 1.1
Past 62, 0.3 10, 0.3 52, 0.3
Monotherapy 187, 0.8 90, 3.1 97, 0.5
Oxcarbazepine 556, 2.5 83, 2.9 473, 2.5 0.137
Current 149, 0.7 27, 0.9 122, 0.6
Past 131, 0.6 20, 0.7 111, 0.6
Monotherapy 66, 0.3 11, 0.4 55, 0.3
Phenobarbital 520, 2.3 85, 3.0 435, 2.2 0.018
Current 205, 0.9 39, 1.4 166, 0.9
Past 124, 0.6 28, 1.0 96, 0.5
Monotherapy 58, 0.3 10, 0.3 48, 0.2
Phenytoin 610, 2.7 128, 4.5 482, 2.5 <0.001
Current 232, 1.0 49, 1.7 183, 0.9
Past 121, 0.5 25, 0.9 96, 0.5
Monotherapy 96, 0.4 17, 0.6 79, 0.4
Pregabalin 9720, 43.6 1100, 38.4 8620, 44.4 <0.001
Current 1829, 8.2 239, 8.3 1590, 8.2
Past 2586, 11.6 285, 9.9 2301, 11.9
Monotherapy 1058, 4.8 119, 4.2 939, 4.8
Topiramate 1088, 4.9 168, 5.9 920, 4.7 0.010
Current 176, 0.8 36, 1.3 140, 0.7
Past 285, 1.3 45, 1.6 240, 1.2
Monotherapy 77, 0.3 9, 0.3 68, 0.4
Valproic acid 1037, 4.7 192, 6.7 845, 4.4 <0.001
Current 367, 1.6 92, 3.2 275, 1.4
Past 214, 1.0 28, 1.0 186, 1.0
Monotherapy 175, 0.8 39, 1.4 136, 0.7