Phenytoin (n = 3917) | Valproic acid (n = 1623) | Carbamazepine (n = 457) | New ASM (n = 965) | P value | |
---|---|---|---|---|---|
Mortality in the follow-up period, n (%) | 237(6.1 %) | 56(3.5 %) | 4(0.9 %) | 23(2.4 %) | < 0.0001 |
Interval from index date of ASM use to death, years, mean (SD) | 0.9(1.1) | 0.8(0.8) | 1.3(1.7) | 0.8(1.0) | 0.5362 |
New ischemic stroke in the follow-up period, n (%) | 83(2.1 %) | 25(1.5 %) | 4(0.9 %) | 20(2.1 %) | < 0.0001 |
Interval from index date of ASM use to new ischemic stroke, years, mean (SD) | 1.6(1.6) | 1.4(1.2) | 0.9(0.6) | 1.4(1.4) | 0.7513 |