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Table 4 Association between heart rate and unfavorable 3-month functional outcomes in the overall cohort

From: Initial in-hospital heart rate is associated with three-month functional outcomes after acute ischemic stroke

HR subgroup

Number of events/at risk, %

Unadjusted

  

Multivariate-adjusted

  
  

OR

95% CI

P value

OR

95% CI

P value

Mean HR

 G1 (< 70 bpm)

119/570 (21)

1.00

Reference

…

1.00

Reference

…

 G2 (≥ 70 and < 80 bpm)

153/404 (38)

2.31

1.74 − 3.07

 < 0.001

1.81

1.25 − 2.61

0.002

 G3 (≥ 80 and < 90 bpm)

129/262 (49)

3.68

2.68 − 5.04

 < 0.001

2.52

1.66 − 3.82

 < 0.001

 G4 (≥ 90 bpm)

134/184 (73)

10.16

6.93 − 14.89

 < 0.001

3.88

2.20 − 6.85

 < 0.001

 P for trend

   

 < 0.001

  

 < 0.001

HR-CV

 G1 (< 0.08)

124/397 (31)

1.00

Reference

…

1.00

Reference

…

 G2 (> 0.08 and < 0.10)

108/305 (35)

1.21

0.88 − 1.66

0.244

1.32

0.87 − 2.00

0.192

 G3 (≥ 0.10 and < 0.12)

94/236 (40)

1.46

1.04 − 2.04

0.028

1.10

0.69 − 1.75

0.700

 G4 (≥ 0.12)

209/482 (43)

1.69

1.28 − 2.23

 < 0.001

1.47

1.00 − 2.16

0.051

 P for trend

   

0.002

  

0.224

  1. Abbreviations: HR heart rate, HR-CV the coefficient of variation of heart rate, CI confidence interval, OR odds ratio