Fig. 1
From: Lacosamide-induced sinus node dysfunction followed by severe agranulocytosis
Clinical course, laboratory, and electrocardiogram findings of the present case. The patient’s clinical course and the chronological changes of HR and WBC counts (upper graph, A), laboratory results of WBC, neutrophils, Hb, Plt, CRP, and BT (lower table, A) are shown. An electrocardiogram finding on the 10th hospital day is also shown with a maximum sinus arrest of 5.6 s (B). Abbreviations: BT = body temperature; CRP = C-reactive protein; G-CSF = granulocyte-colony stimulating factor; Hb = hemoglobin; HR = heart rate; LCM = lacosamide; LEV = levetiracetam; MEPM = meropenem; NE = not examined; PHT = phenytoin; Plt = platelet; RCC = red blood cell concentrates; SND = sinus node dysfunction; VCM = vancomycin; WBC = white blood cell