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Fig. 3 | BMC Neurology

Fig. 3

From: Steroid responsive cavernous sinus syndrome due to Rosai-Dorfman disease: beyond Tolosa-Hunt syndrome – a case report

Fig. 3

 A- HE staining, 10x low magnification: Histological specimen show sections of fibrous and thickened dura mater (blue arrow) with extensive superficial infiltration by histiocytic cells (black arrow). B - HE staining, 20x intermediate magnification Histological sections show extensive superficial meningeal infiltration by histiocytes ( arrow ); absence of cell atypias, malignant cells or meningothelial neoplasia. C - Immunohistochemical reaction for CD68: diffuse positivity in lesion cells, confirming histiocytic aspect. D - Immunohistochemical reaction for S100: focal positivity in lesion cells, confirming histiocytic aspect. Other reactions performed were negative: CD1a and ALK (not shown)

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BMC Neurology

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