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Table 3 Patients characteristics and results from sarcopenia assessment

From: Late-onset neuromuscular disorders in the differential diagnosis of sarcopenia

  Sarcopenia
n = 1
ALS
n = 1
IBM
n = 1
DM2
n = 1
Thresholds
[1, 20,21,22, 24]
Age [years] 85 68 80 80  
Female No No Yes No  
BMI [kg/m2] 22.5 16.6 19.5 30.9  < 23 = underweight
23–30 = normal
 > 30 = overweight
Diagnostic delaya [years] 20 7 8 5  
IADL-Score 4 2 5 0 8 = highly independent
0 = highly dependant
MNA®SF-Score 10 6 9 10  > 11: normal
11–8: risk of malnutrition
 ≤ 7: malnutrition
SARC-F Score 7 10 9 6  ≥ 4 possible sarcopenia
Maximum HGS [kg] 19.4 21.2 7.8 20.4 Female: 16; Male: 27
HGSo [kg] 19.2 15.4 4.7 20.0
HGSo / maximum HGS [%] 99 73 60 98
SMI [kg/m2] 6.6 5.5 3.9 6.9 Female: 5.5; Male: 7.0
Gaitspeed [m/s] b 0.4 0.1 0.3 0.8
CK [U/L] 96 410 390 160 Reference <  = 169
  1. BMI body mass index, DM2 myotonic dystrophy type 2, HGS hand grip strength, HGSo and grip strength, other Hand, IADL instrumental activities of daily living, MNA®-SF mini nutritional assessment short form, ALS amyotrophic lateral sclerosis; SMI = skeletal muscle mass index, CK serum creatine kinase, IBM inclusion body myositis
  2. atime from first reported symptoms to diagnose; b due to surgery no valid gait speed assessment possible