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Table 3 Patients characteristics and results from sarcopenia assessment

From: Late-onset neuromuscular disorders in the differential diagnosis of sarcopenia

 

Sarcopenia

n = 1

ALS

n = 1

IBM

n = 1

DM2

n = 1

Thresholds

[1, 20,21,22, 24]

Age [years]

85

68

80

80

 

Female

No

No

Yes

No

 

BMI [kg/m2]

22.5

16.6

19.5

30.9

 < 23 = underweight

23–30 = normal

 > 30 = overweight

Diagnostic delaya [years]

20

7

8

5

 

IADL-Score

4

2

5

0

8 = highly independent

0 = highly dependant

MNA®SF-Score

10

6

9

10

 > 11: normal

11–8: risk of malnutrition

 ≤ 7: malnutrition

SARC-F Score

7

10

9

6

 ≥ 4 possible sarcopenia

Maximum HGS [kg]

19.4

21.2

7.8

20.4

Female: 16; Male: 27

HGSo [kg]

19.2

15.4

4.7

20.0

HGSo / maximum HGS [%]

99

73

60

98

SMI [kg/m2]

6.6

5.5

3.9

6.9

Female: 5.5; Male: 7.0

Gaitspeed [m/s]

b

0.4

0.1

0.3

0.8

CK [U/L]

96

410

390

160

Reference <  = 169

  1. BMI body mass index, DM2 myotonic dystrophy type 2, HGS hand grip strength, HGSo and grip strength, other Hand, IADL instrumental activities of daily living, MNA®-SF mini nutritional assessment short form, ALS amyotrophic lateral sclerosis; SMI = skeletal muscle mass index, CK serum creatine kinase, IBM inclusion body myositis
  2. atime from first reported symptoms to diagnose; b due to surgery no valid gait speed assessment possible