From: Construction of a risk prediction model for Alzheimer’s disease in the elderly population
Characteristics | Participants (n = 1099) | With AD (n = 555) | Without AD (n = 544) | Training set (n = 824) | Validation set (n = 275) | P-value |
---|---|---|---|---|---|---|
Age (year) | 66.85 ± 4.07 | 67.06 ± 4.23 | 66.62 ± 3.88 | 66.82 ± 4.01 | 66.94 ± 4.23 | 0.047 |
Sex, n (%) | 0.039 | |||||
Male | 711 (64.70) | 362 (65.23) | 349 (64.15) | 543 (65.9) | 168 (61.09) | |
Female | 388 (35.30) | 193 (34.77) | 195 (35.85) | 281 (34.1) | 107 (38.91) | |
BMI (kg/m2) | 23.14 ± 2.84 | 23.19 ± 2.91 | 23.15 ± 2.65 | 23.17 ± 2.86 | 23.06 ± 2.78 | 0.605 |
Marital status, n (%) | 0.302 | |||||
1 | 360 (32.76) | 179 (32.25) | 181 (33.27) | 266 (32.28) | 94 (34.18) | |
2 | 349 (31.76) | 166 (29.91) | 183 (33.64) | 264 (32.04) | 85 (30.91) | |
3 | 390 (35.49) | 210 (37.84) | 180 (33.09) | 294 (35.68) | 96 (34.91) | |
Education level, n (%) | 0.051 | |||||
1 | 454 (41.31) | 257 (46.31) | 197 (36.21) | 340 (41.26) | 114 (41.45) | |
2 | 205 (18.65) | 64 (11.53) | 141 (25.92) | 153 (18.57) | 52 (18.91) | |
3 | 440 (40.04) | 234 (42.16) | 206 (37.87) | 331 (40.17) | 109 (39.64) | |
Economic status, n (%) | < 0.001 | |||||
1 | 336 (30.57) | 209 (37.66) | 127 (23.35) | 253 (30.7) | 83 (30.18) | |
2 | 203 (18.47) | 97 (17.48) | 106 (19.49) | 152 (18.45) | 51 (18.55) | |
3 | 172 (15.65) | 79 (14.23) | 93 (17.1) | 133 (16.14) | 39 (14.18) | |
4 | 160 (14.56) | 67 (12.07) | 93 (17.1) | 117 (14.2) | 43 (15.64) | |
5 | 228 (20.75) | 103 (18.56) | 125 (22.98) | 169 (20.51) | 59 (21.45) | |
Lifestyle, n (%) | 0.038 | |||||
1 | 359 (32.67) | 193 (34.77) | 166 (30.51) | 266 (32.28) | 93 (33.82) | |
2 | 349 (31.76) | 166 (29.91) | 183 (33.64) | 264 (32.04) | 85 (30.91) | |
3 | 153 (13.92) | 78 (14.05) | 75 (13.79) | 114 (13.83) | 39 (14.18) | |
4 | 146 (13.28) | 86 (15.5) | 60 (11.03) | 112 (13.59) | 34 (12.36) | |
5 | 92 (8.37) | 32 (5.77) | 60 (11.03) | 68 (8.25) | 24 (8.73) | |
Health status, n (%) | 0.025 | |||||
1 | 294 (26.75) | 163 (29.37) | 131 (24.08) | 216 (26.21) | 78 (28.36) | |
2 | 258 (23.48) | 131 (23.6) | 127 (23.35) | 193 (23.42) | 65 (23.64) | |
3 | 213 (19.38) | 107 (19.28) | 106 (19.49) | 158 (19.17) | 55 (20) | |
4 | 188 (17.11) | 91 (16.4) | 97 (17.83) | 145 (17.6) | 43 (15.64) | |
5 | 146 (13.28) | 63 (11.35) | 83 (15.26) | 112 (13.59) | 34 (12.36) | |
Genetic risk, n (%) | 0.019 | |||||
1 | 151 (13.74) | 77 (13.87) | 74 (13.6) | 117 (14.2) | 34 (12.36) | |
2 | 482 (43.86) | 220 (39.64) | 262 (48.16) | 362 (43.93) | 120 (43.64) | |
3 | 466 (42.40) | 258 (46.49) | 208 (38.24) | 345 (41.87) | 121 (44) |