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Table 6 Correlation analysis between serum antibody marker levels and sex, other diseases, lifestyle, and obesity

From: Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction

  

ALDOA-Ab

FH-Ab

Sex

 

Male

Female

Male

Female

Sample number

 

692

458

692

458

Antibody level

Average

19,087

18,196

3,323

3,492

SD

11,046

10,456

3,258

3,630

P value (vs Male)

  

0.1941

 

0.2563

DM

 

DM (–)

DM ( +)

DM (–)

DM ( +)

Sample number

 

926

219

926

219

Antibody level

Average

18,637

19,189

3,315

3,710

SD

11,045

9,902

3,425

3,349

P value [vs DM (–)]

  

0.1250

 

0.0183

Blood pressure

 

HT (–)

HT ( +)

HT (–)

HT ( +)

Sample number

 

505

640

505

640

Antibody level

Average

17,927

19,388

2,977

3,717

SD

11,037

10,635

2,985

3,685

P value [vs HT (–)]

  

0.0022

 

 < 0.0001

CHD

 

CHD (–)

CHD ( +)

CHD–

CHD + 

Sample number

 

1086

59

1086

59

Antibody level

Average

18,600

21,373

3,336

4,397

SD

10,685

13,087

3,351

4,302

P value [vs CHD (–)]

  

0.0400

 

0.0268

Lipidemia

 

HL (–)

HL ( +)

HL (–)

HL ( +)

Sample number

 

844

301

844

301

Antibody level

Average

18,871

18,384

3,514

3,045

SD

11,144

9,923

3,688

2,455

P value [vs HL (–)]

 

0.6244

 

0.6545

Life style

 

Non-smoker

Smoker

Non-smoker

Smoker

Sample number

 

584

561

584

561

Antibody level

Average

17,371

20,158

3,282

3,494

SD

9,641

11,783

3,587

3,186

P value (vs non-smoker)

 

 < 0.0001

 

0.0566

Life style

 

Alcohol (–)

Alcohol ( +)

Alcohol (–)

Alcohol ( +)

Sample number

 

338

570

338

570

Antibody level

Average

17,928

19,507

3,528

3,466

SD

9,311

12,373

3,544

3,492

P value [vs Alcohol (-)]

  

0.0817

 

0.8972

Obesity

 

BMI < 25

BMI ≥ 25

BMI < 25

BMI ≥ 25

Sample number

 

809

315

809

315

Antibody level

Average

18,911

18,568

3,577

2,992

SD

11,198

10,049

3,722

2,475

P value (vs BMI < 25)

  

0.8354

 

0.0720

  1. The subjects were divided into two groups as follows: sex (male and female); presence ( +) or absence ( −) of complication of DM, HT, CHD or hyperlipidemia (HL), lifestyle factors (smoking and alcohol intake habits), and obesity. Antibody levels (alpha counts) were compared using the Mann–Whitney U test. Sample numbers, averages and SDs of counts as well as P values are shown. Significant correlations (P < 0.05) are marked in bold