Skip to main content

Table 6 Correlation analysis between serum antibody marker levels and sex, other diseases, lifestyle, and obesity

From: Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction

   ALDOA-Ab FH-Ab
Sex   Male Female Male Female
Sample number   692 458 692 458
Antibody level Average 19,087 18,196 3,323 3,492
SD 11,046 10,456 3,258 3,630
P value (vs Male)    0.1941   0.2563
DM   DM (–) DM ( +) DM (–) DM ( +)
Sample number   926 219 926 219
Antibody level Average 18,637 19,189 3,315 3,710
SD 11,045 9,902 3,425 3,349
P value [vs DM (–)]    0.1250   0.0183
Blood pressure   HT (–) HT ( +) HT (–) HT ( +)
Sample number   505 640 505 640
Antibody level Average 17,927 19,388 2,977 3,717
SD 11,037 10,635 2,985 3,685
P value [vs HT (–)]    0.0022    < 0.0001
CHD   CHD (–) CHD ( +) CHD– CHD + 
Sample number   1086 59 1086 59
Antibody level Average 18,600 21,373 3,336 4,397
SD 10,685 13,087 3,351 4,302
P value [vs CHD (–)]    0.0400   0.0268
Lipidemia   HL (–) HL ( +) HL (–) HL ( +)
Sample number   844 301 844 301
Antibody level Average 18,871 18,384 3,514 3,045
SD 11,144 9,923 3,688 2,455
P value [vs HL (–)]   0.6244   0.6545
Life style   Non-smoker Smoker Non-smoker Smoker
Sample number   584 561 584 561
Antibody level Average 17,371 20,158 3,282 3,494
SD 9,641 11,783 3,587 3,186
P value (vs non-smoker)    < 0.0001   0.0566
Life style   Alcohol (–) Alcohol ( +) Alcohol (–) Alcohol ( +)
Sample number   338 570 338 570
Antibody level Average 17,928 19,507 3,528 3,466
SD 9,311 12,373 3,544 3,492
P value [vs Alcohol (-)]    0.0817   0.8972
Obesity   BMI < 25 BMI ≥ 25 BMI < 25 BMI ≥ 25
Sample number   809 315 809 315
Antibody level Average 18,911 18,568 3,577 2,992
SD 11,198 10,049 3,722 2,475
P value (vs BMI < 25)    0.8354   0.0720
  1. The subjects were divided into two groups as follows: sex (male and female); presence ( +) or absence ( −) of complication of DM, HT, CHD or hyperlipidemia (HL), lifestyle factors (smoking and alcohol intake habits), and obesity. Antibody levels (alpha counts) were compared using the Mann–Whitney U test. Sample numbers, averages and SDs of counts as well as P values are shown. Significant correlations (P < 0.05) are marked in bold