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Table 1 Summary of included studies

From: Intraoperative monitoring of visual evoked potentials in patients undergoing transsphenoidal surgery for pituitary adenoma: a systematic review

Study Study design Patients Number of patients with Pituitary Adenoma Types of Pituitary Adenoma Average size of tumour (cm)
Feng et al. (2019)a [18] Case series 42 pts with primary sellar neoplasms undergoing endoscopic TSS 40 Non-functioning: 32
GH-secreting: 5
Prolactinoma: 3
Non-secretory: 2.81 ± 1.10
Secretory: 3.29 ± 1.80
Other: 1.55 ± 0.64
Overall: 2.84 ± 1.23
Qiao et al. (2019) [19] Case series 76 patients with sellar region tumour undergoing TSS
(152 eyes tested)
Not reported Not reported Not reported
Toyama et al. (2018) [20] Case series 20 pts undergoing endoscopic TSS
(39 eyes tested)
16 Not reported 2.79 (range 1.5–4.5)
Nishimura et al. (2018) [21] Case series 82 pts undergoing endoscopic TSS
(164 eyes tested)
Not reported Not reported Not reported
Kurozumi et al.a (2017) [22] Case series 19 pts with sellar/parasellar tumours undergoing endoscopic TSS 17 Non-functioning: 14
GH-secreting: 3
Not reported
Luo et al. (2015) [23] Case series 46 pts undergoing cranial surgery or TSS
(85 eyes tested)
12 Not reported Not reported
Kamio et al.a (2014) [7] Case series 33 pts with sellar or parasellar tumours undergoing TSS 25 Not reported Not reported
Houlden et al.a (2014 [9] Case series 10 pts undergoing TSS for tumours near optic nerve or chiasm
2 pts undergoing craniotomy for an occipital lobe tumour and glial based tumour
Not reported Not reported Not reported
Chung et al. (2012) [24] Case Series 53 pts with sellar or parasellar lesions undergoing endoscopic TSS
(106 eyes tested)
37 Not reported Not reported
Sasaki et al. (2010) [6] Case Series 100 pts at intraoperative risk of visual impairment including 28 pts with parasellar lesions
(200 eyes tested)
Not reported Not reported Not reported
Chacko et al. (1996) [25] Cohort 36 pts undergoing TSS for pituitary adenomas; 22 with VEP monitoring, 14 without
(72 eyes tested; 44 with VEP monitoring, 28 without)
36 Not reported Not reported
  1. pts patients, TSS Transsphenoidal surgery
  2. a These studies did not comment on individual eyes tested