Table 2 Univariable and multivariable linear regression for change in EDSS (EDSS2–EDSS1) with combined patients from Canada and Saudi Arabia (n = 98)
Variables | Univariable | Multivariable | ||||
|---|---|---|---|---|---|---|
Coef | 95% CI | P-value | Coef | 95% CI | P-value | |
Indicator (Canada = 0, Saudi = 1) | 0.204 | 0.042,0.366 | 0.014 | 0.410 | 0.173, 0.648 | 0.001 |
Age of onset (yr.) | 0.00311 | - | NS | 0.0146 | 0.0043, 0.0248 | 0.006 |
Sex (Female = 0, Male = 1) | 0.167 | - | NS | 0.0905 | - | NS |
Family History (N = 0, Y = 1) | -0.136 | - | NS | -0.273 | - | NS |
Duration of disease (yr.) | -0.0130 | - | NS | 0.0124 | - | NS |
Smoking (N = 0, Y = 1) | 0.0563 | - | NS | 0.220 | 0.029, 0.411 | 0.025 |
Asthma (N = 0, Y = 1) | 0.130 | - | NS | 0.269 | - | NS |
Hypertension/diabetes mellitus (N = 0, Y = 1) | 0.0431 | - | NS | -0.456 | -0.755, -0.156 | 0.003 |
Glucocorticoid therapy (N = 0, Y = 1) | 0.0307 | - | NS | -0.329 | -0.645, -0.013 | 0.041 |
Motor episode (N = 0, Y = 1) | 0.241 | 0.072, 0.412 | 0.006 | 0.567 | 0.346, 0.787 | < 0.001 |
Sensory episode (N = 0, Y = 1) | 0.0224 | - | NS | 0.298 | 0.111, 0.485 | 0.002 |
Brainstem episode (N = 0, Y = 1) | 0.0206 | - | NS | 0.246 | 0.026, 0.466 | 0.029 |
Mental episode (N = 0, Y = 1) | 0.376 | - | NS | 0.852 | 0.086, 1.618 | 0.030 |
Bowel and bladder episode (N = 0, Y = 1) | 0.170 | - | NS | 0.318 | 0.013, 0.624 | 0.041 |
Visual episode (N = 0, Y = 1) | -0.0160 | - | NS | 0.161 | - | NS |
Myelopathic episode (N = 0, Y = 1) | -0.138 | - | NS | 0.464 | 0.166, 0.763 | 0.003 |
Brainstem functional scale (N = 0, Y = 1) | 0.200 | 0.036, 0.364 | 0.018 | 0.356 | 0.174, 0.538 | < 0.001 |
Visual functional scale (N = 0, Y = 1) | -0.0166 | - | NS | 0.231 | 0.022, 0.442 | 0.031 |