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Table 1 Background and diagnostic factors in all 277 cases and their relationship to patient prognoses

From: Maximum resection and immunotherapy improve glioblastoma patient survival: a retrospective single-institution prognostic analysis

Factors

 

Patient numbers

 

Median PFS (months)

P values

Median OS (months)

P values

All cases

 

277

 

8.7

 

16.6

 

Age

Median (percentile)

66

(57–74)

    

66 or more

149

(53.8%)

8.2

0.334

13.8

0.006

65 or less

128

(46.2%)

9.4

19.3

Sex

Men (%)

165

(59.6%)

8.4

0.281

16.6

0.966

Women

112

(40.4%)

8.7

15.7

Main Location

Frontal

103

(37.2%)

8.6

0.395

16.2

0.179

Temporal

93

(33.6%)

8.3

15.1

Parieto-Occipital

40

(14.4%)

9.2

24.8

Others

41

(14.8%)

9.8

15.7

Side

Right

132

(47.7%)

9.8

0.030

19.1

0.013

Left

118

(42.6%)

8.2

15.9

Others

27

(9.7%)

5.1

11.0

KPS

Median (percentile)

70

(60–80)

    

70 or more

190

(68.6%)

9.2

0.190

19.7

0.006

60 or less

87

(31.4%)

8.6

11.2

EOR

Non-biopsy

200

(72.2%)

9.5

 

19.7

 

GTR (100% of EOR)

91

(32.9%)

11.3

0.000

26.5

0.000

STR

58

(20.9%)

9.2

21.7

PR

51

(18.4%)

5.3

11.1

Biopsy

77

(27.8%)

7.1

9.7

5-ALA

Strong

190

(68.6%)

9.1

0.096

16.8

0.300

Vague

31

(11.2%)

6.7

14.4

Positive

11

(4.0%)

11.5

18.0

Negative

8

(2.9%)

10.3

13.7

Not used/Unknown

37

(13.4%)

4.9

16.7

Intraoperative

MRI

Yes (for removal)

82

(29.6%)

11.2

0.009

21.7

0.000

Yes (for biopsy)

12

(4.3%)

6.4

8.2

Not used

183

(66.1%)

8.1

14.7