Fig. 2

TMS-Induced Connectivity is Task Dependent in the Healthy Brain but not in Stroke. M1 = Primary Motor Cortex. *p = .03. The ΔC measures how the influence of the stimulated motor cortex over the recorded hemisphere changes with hand movement. Task Motor Cortex stimulation is shown in the left box. With hand movement in controls, the influence of the task motor cortex differs between the hemispheres: increased connectivity is seen within the task hemisphere (blue circles) while decreased connectivity is seen in the passive hemisphere (red triangles). With paretic hand movement in stroke patients, a similar but non-significant pattern emerges. Passive Motor Cortex stimulation is shown in the right box. Hand-movement induced connectivity differences between the hemispheres are not seen with TMS to the passive motor cortex in either group