Fig. 2

Pre-operative thalamus volume in healthy controls (HC) and TN patients sorted by surgical outcome. There is no difference between HC thalamus volume (average of left and right thalamus) and ipsilateral or contralateral thalamus volume for either responders (Res—light grey bars) or non-responders (Non-Res—dark grey bars). (A) The contralateral thalamus is larger than the ipsilateral thalamus in both responders and non-responders. No differences were observed in thalamus volume between responders and non-responders, either ipsilaterally or contralaterally. (B) There is also no difference in left vs. right thalamus interhemispheric % volume difference between responders and non-responders. Mann–Whitney tests were used to perform between-group comparisons, while Wilcoxon sign-rank tests were used to compare thalamus volumes within-groups. Statistical significance (p < 0.05) is indicated with *. Medians with interquartile ranges are displayed