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Fig. 4 | BMC Neurology

Fig. 4

From: The thalamus in trigeminal neuralgia: structural and metabolic abnormalities, and influence on surgical response

Fig. 4

Pre-operative thalamus Cho/Cr and NAA/Cr in healthy controls (HC) and TN patients sorted by side-of-pain. (A) There is no difference in Cho/Cr between the left and right thalamus within healthy controls (HC), left-sided TN patients (LTN), or right-sided TN patients (RTN). Additionally, there is no difference in thalamus Cho/Cr between any of these groups. (C) Left NAA/Cr is increased in HC compared to RTN (p = 0.050). NAA/Cr of the left thalamus is increased in LTN patients compared to both the left (p = 0.029) and right (p = 0.010) thalamus of RTN patients. Left vs. right interhemispheric % difference for Cho/Cr (B) or NAA/Cr (D) does not differ between left healthy controls (LHC) and LTN or right healthy controls (RHC) and RTN. Mann–Whitney tests were used to perform between-group comparisons, while Wilcoxon sign-rank tests were used to compare thalamus volumes within-groups. Statistical significance (p < 0.05) is indicated with *. Medians with interquartile ranges are displayed

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