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Table 1 Baseline and three-month characteristics of the study population compared to the remaining Nor-COAST population

From: Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study

 

Total n = 700

Not included (n = 443)

Included (n = 257)

p

Sex, male, n (%)

251 (57)

149 (58)

0.734

Age at three months, mean y (SD)

74 (12)

73 (11)

0.162

BMI at three months, mean kg/m2 (SD)

27 (4.2)

27 (4.3)

0.797

Waist at three months, mean cm (SD)

97 (13)

95 (13)

0.283

NIHSS on admission, mean (SD)

5.0 (6.5)

3.7 (4.6)

0.004

 At three months

1.0 (2.0)

0.7 (1.3)

0.022

Modified Rankin scale, mean (SD)

2.5 (1.5)

2.0 (1.1)

< 0.001

 At three months

2.0 (1.4)

1.5 (0.9)

< 0.001

Modified Rankin scale ≤2, n (%)

269 (49)

178 (70)

< 0.001

 At three months

304 (68)

224 (88)

< 0.001

Barthel index, mean (SD)

79 (28)

92 (14)

< 0.001

 At three months

90 (21)

98 (6.1)

< 0.001

Laboratory values at three months*, median (IQR)

 eGFR (N = 272/253)

77 (60, 89)

76 (63, 88)

0.696

 hsCRP (N = 98/169)

1.9 (0.7, 3.6)

1.6 (0.8, 3.7)

0.513

 IL6 (N = 111/257)

4.6 (2.5, 6.7)

4.6 (2.9, 7.4)

0.438

 IL10 (N = 111/257)

18 (8.6, 32)

20 (8.6, 36)

0.304

 Neopterin (N = 109/257)

16 (12, 22)

16 (12, 22)

0.998

 PAr-index (N = 109/257)

0.52 (0.39, 0.73)

0.64 (0.44, 0.91)

0.005

 KTR (N = 109/257)

32 (28, 40)

34 (29, 42)

0.062

 KA (N = 109/257)

55 (44, 75)

59 (46, 76)

0.276

  1. *Number of patients attending baseline and three months: A total of 558 patients had blood samples taken at three months. Of these, 368 had biobank samples taken. The N for each individual biomarker is shown for each group (not included/included)