Table 1 Clinical and sociodemographic characteristics of the study population
Total, n = 2009 | |
|---|---|
Age, years, mean (SD) | 49.4 (12.1) |
Sex, female, n (%) | 1389 (69.1) |
Diagnosis, n (%) | |
Multiple sclerosis | 1979 (98.5) |
CIS (clinical isolated syndrome) | 30 (1.5) |
Clinical type of MS, n (%) | |
Relapse-remitting MS (RRMS) | 1383 (69.9) |
Secondary progressive MS (SPMS) | 153 (7.7) |
Primary progressive MS (PPMS) | 153 (7.7) |
Unaware | 290 (14.7) |
Age at diagnosis, mean (SD) | 37.7 (10.9) |
Duration of diagnosis, years, mean (SD) | 11.7 (8.1) |
Current DMT, n (%) | 1502 (75) |
Duration of DMT use, years, median (ICR) | 9 (4–14) |
Quality of life, NRS-111, mean (SD) | |
Satisfaction with life situation | 6.5 (2.5) |
Satisfaction with physical health | 5.6 (2.8) |
Satisfaction with mental health | 6.5 (2.6) |
Sleep disturbances, NRS-112, mean (SD) | 4.2 (2.8) |
FSS score, median (range) | 43 (54) |
No to mild fatigue (FSS score < 36), n (%) | 728 (36) |
Moderate fatigue (FSS score 36–52), n (%) | 679 (34) |
Severe fatigue (FSS score > 52), n (%) | 602 (30) |
Chronic pain, n (%) | 763 (38.0) |
Pain intensity, NRS-113, mean (SD) | 5.2 (2.2) |
Drug treatment for pain, n (%) | 368 (48.4) |
Spasticity, n (%) | 1025 (51.0) |
Spasm intensity, NRS-114, mean (SD) | 3.6 (2.4) |
Drug treatment for spasticity, n (%) | 352 (35.8) |
PDDS level, median (ICR) | 2.0 (0–4) |
PDDS levels (0 to 8), n (%) | |
0 Normal | 663 (33) |
1 Mild | 307 (15) |
2 Moderate | 280 (14) |
3 Gait disabilities | 243 (12) |
4 Early cane | 183 (9.1) |
5 Late cane | 94 (4.6) |
6 Bilateral support | 110 (5.6) |
7 Wheelchair | 114 (5.7) |
8 Bedridden | 15 (1.0) |
Bowel and bladder function, n (%) | |
Normal | 729 (36.3) |
Mild dysfunction | 722 (35.9) |
Moderate dysfunction | 343 (17.1) |
Severe dysfunction | 114 (5.7) |
Lost bowel or bladder function | 54 (2.7) |
Lost bowel and bladder function | 47 (2.3) |
BMI, mean (SD) | 25.1 (5.1) |
Smoking status, n (%) | |
Daily | 361 (18.0) |
Occasional | 117 (5.8) |
Former smoker | 819 (40.8) |
Never smoker | 712 (35.4) |
Occupation, n (%) | |
Employed full-time | 718 (35.7) |
Employed part-time | 486 (24.2) |
Unemployed | 805 (40.1) |
Personal income pr. year, n (%) | |
< $30,000 | 467 (23.3) |
$30,000 - $59,999 | 797 (39.7) |
$60,000 - $105,000 | 498 (24.8) |
> $105,000 | 123 (6.2) |
Unaware | 121 (6.0) |
Family status, n (%) | |
Married/cohabiting living without children | 745 (37.1) |
Married/cohabiting living with children | 625 (31.2) |
Living alone with children | 174 (8.7) |
Living alone without children | 462 (23.0) |
Education, n (%) | |
Below high-school graduate | 149 (7.4) |
High-school graduate | 158 (7.9) |
Skilled education | 414 (20.7) |
Shorter courses | 25 (1.2) |
Short post-secondary education | 235 (11.7) |
Middle post-secondary education | 560 (28.0) |
Long post-secondary education | 464 (23.1) |