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Table 1 Clinical and sociodemographic characteristics of the study population

From: The association of selected multiple sclerosis symptoms with disability and quality of life: a large Danish self-report survey

  Total,
n = 2009
Age, years, mean (SD) 49.4 (12.1)
Sex, female, n (%) 1389 (69.1)
Diagnosis, n (%)
 Multiple sclerosis 1979 (98.5)
 CIS (clinical isolated syndrome) 30 (1.5)
Clinical type of MS, n (%)
 Relapse-remitting MS (RRMS) 1383 (69.9)
 Secondary progressive MS (SPMS) 153 (7.7)
 Primary progressive MS (PPMS) 153 (7.7)
 Unaware 290 (14.7)
Age at diagnosis, mean (SD) 37.7 (10.9)
Duration of diagnosis, years, mean (SD) 11.7 (8.1)
Current DMT, n (%) 1502 (75)
Duration of DMT use, years, median (ICR) 9 (4–14)
Quality of life, NRS-111, mean (SD)
 Satisfaction with life situation 6.5 (2.5)
 Satisfaction with physical health 5.6 (2.8)
 Satisfaction with mental health 6.5 (2.6)
Sleep disturbances, NRS-112, mean (SD) 4.2 (2.8)
FSS score, median (range) 43 (54)
 No to mild fatigue (FSS score < 36), n (%) 728 (36)
 Moderate fatigue (FSS score 36–52), n (%) 679 (34)
 Severe fatigue (FSS score > 52), n (%) 602 (30)
Chronic pain, n (%) 763 (38.0)
Pain intensity, NRS-113, mean (SD) 5.2 (2.2)
Drug treatment for pain, n (%) 368 (48.4)
Spasticity, n (%) 1025 (51.0)
Spasm intensity, NRS-114, mean (SD) 3.6 (2.4)
Drug treatment for spasticity, n (%) 352 (35.8)
PDDS level, median (ICR) 2.0 (0–4)
PDDS levels (0 to 8), n (%)
 0 Normal 663 (33)
 1 Mild 307 (15)
 2 Moderate 280 (14)
 3 Gait disabilities 243 (12)
 4 Early cane 183 (9.1)
 5 Late cane 94 (4.6)
 6 Bilateral support 110 (5.6)
 7 Wheelchair 114 (5.7)
 8 Bedridden 15 (1.0)
Bowel and bladder function, n (%)
 Normal 729 (36.3)
 Mild dysfunction 722 (35.9)
 Moderate dysfunction 343 (17.1)
 Severe dysfunction 114 (5.7)
 Lost bowel or bladder function 54 (2.7)
 Lost bowel and bladder function 47 (2.3)
BMI, mean (SD) 25.1 (5.1)
Smoking status, n (%)
 Daily 361 (18.0)
 Occasional 117 (5.8)
 Former smoker 819 (40.8)
 Never smoker 712 (35.4)
Occupation, n (%)
 Employed full-time 718 (35.7)
 Employed part-time 486 (24.2)
 Unemployed 805 (40.1)
Personal income pr. year, n (%)
  < $30,000 467 (23.3)
 $30,000 - $59,999 797 (39.7)
 $60,000 - $105,000 498 (24.8)
  > $105,000 123 (6.2)
 Unaware 121 (6.0)
Family status, n (%)
 Married/cohabiting living without children 745 (37.1)
 Married/cohabiting living with children 625 (31.2)
 Living alone with children 174 (8.7)
 Living alone without children 462 (23.0)
Education, n (%)
 Below high-school graduate 149 (7.4)
 High-school graduate 158 (7.9)
 Skilled education 414 (20.7)
 Shorter courses 25 (1.2)
 Short post-secondary education 235 (11.7)
 Middle post-secondary education 560 (28.0)
 Long post-secondary education 464 (23.1)
  1. NRS-11, numeric rating scale (from 0 to 10); FSS, fatigue severity scale;
  2. PDDS, patient determined disease steps; SD, standard deviation
  3. 1 0 = completely dissatisfied to 10 = completely satisfied
  4. 2 0 = no disturbances to 10 = high disturbed sleep
  5. 3 0 = no pain to 10 = worst imaginable pain
  6. 4 0 = no spasticity to 10 = worst possible spasticity
  7. ICR, interquartile range (25–75%)