Table 5 Adverse events in the safety population (n = 492)
Number (%) of patients with AEs | ||
|---|---|---|
Aged 41–50 years (n = 334) | Aged > 50 years (n = 158) | |
Any AE | 50 (15 %) | 31 (19.6 %) |
Any MS-related AE | 22 (6.6 %) | 4 (2.5 %) |
Any severe AE | 11 (3.3 %) | 6 (3.8 %) |
Any serious AE | 14 (4.2 %) | 2 (1.3 %) |
Any AE related to study drug | 32 (9.6 %) | 21 (13.3 %) |
Any serious AE related to study drug | 4 (1.2 %) | 0 (0.0 %) |
Deaths | 3 (0.9 %) | 2 (1.3 %) |
Deaths related to study drug | 0 (0.0 %) | 0 (0.0 %) |