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Table 1 Laboratory investigations

From: Guillain-Barré syndrome as the first presentation of human immunodeficiency virus infection

Sample Parameters evaluated Value
Blood Aspartate-aminotransferase (ALT) 190 U/L (3xULN)
Alanine-aminotransferase (AST) 112 U/L (3 × ULN)
γ-glutamyl transpeptidase 192 (N < 55 U/L)
Hemoglobin, blood glucose, uremia, creatinine, ions, alkaline phosphatase, total bilirubin,lactic dehydrogenase (LDH), creatine-phosphokinase, C-reactive protein, immunoglobulins (total IgG, IgM, IgA), coagulation tests Negative or within normal ranges
Antinuclear antibodies and Antiganglioside antibodies Negative
HIV antigen/antibody (Ag/Ab) test
˗ CD4+ cell count and %
˗ CD4+/CD8+ ratio
˗ HIV viral load
˗ HLA-B*57:01
219/mL; 22.8%
97,800 copies/mL
Hepatitis B virus markers HBsAb positive, total HBcAb, and HBsAg: negative
Hepatitis C Virus-Ab Negative
Syphilis screening Negative
Cytomegalovirus (CMV), Epstein–Barr virus (EBV), herpes simplex virus (HSV) 1/2 IgG Ab positive
Cerebrospinal Fluid (first sample) Cells 1/mm3
Proteins 35 mg/dL
Glucose 71 mg/dL (95 mg/dL blood glucose)
Oligoclonal IgG bands, testing for JC virus and cryptococcus,
Meningitis/Encephalitis Panel
HIV viral load 13,200 copies/mL
Cerebrospinal Fluid (a week after) Cells 1/mm3
Proteins 68 mg/dL
Glucose 70 mg/dL (94 mg/dL blood glucose)
Culture for bacteria and fungi Negative