Associations of the cerebrospinal fluid hepatocyte growth factor with Alzheimer’s disease pathology and cognitive function

Table 2 Demographic characteristics for the non-demented participants

Characteristics	Group A	Group B	Group C	P
N	84	85	69
Age (Mean ± SD, year)	74.52 ± 6.65	73.92 ± 6.18	77.30 ± 6.60	0.0038
Sex (Female, %)	39 (46.4)	30 (35.3)	23 (33.3)	0.1872
Education (Mean ± SD, year)	15.73 ± 2.94	15.67 ± 3.13	16.08 ± 2.71	0.6551
APOE ε4 carrier status (Yes, %)	33 (39.3)	33 (38.8)	35 (50.7)	0.5560
WMHV (Mean ± SD, cm³)	1.03 ± 3.49	0.52 ± 0.92	0.87 ± 1.98	0.076
CSF HGF (Mean ± SD, ng/ml)	0.25 ± 0.09	0.44 ± 0.04	0.62 ± 0.07	< 0.0001

All participants were grouped by tertiles of CSF HGF at baseline. Group A lowest tertile; Group B middle tertile; Group C highest tertile. ANOVA, non-parametric Kruskal-Wallis H test, and Chi-squared test were used to compare the baseline demographic and clinical characteristics. Abbreviations: WMHV white matter hyperintensities volume; CSF cerebrospinal fluid; HGF Hepatocyte Growth Factor

ISSN: 1471-2377