Comparison group | MS group 1 (EDSS 0.0–1.0) | MS group 2 (EDSS 1.5-2.0) | MS group 3 (EDSS 2.5-5.0) | |
---|---|---|---|---|
mean gait parameter | ||||
walking speed [m/s] | 1.67 ± 0.18 | 1.55 ± 0.17 | 1.47 ± 0.19 a | 1.30 ± 0.25 a,b,c |
stride length [m] | 1.61 ± 0.16 | 1.52 ± 0.13 | 1.47 ± 0.13 a | 1.33 ± 0.20 a,b,c |
stride time [s] | 0.96 ± 0.06 | 0.99 ± 0.07 | 1.01 ± 0.07 | 1.04 ± 0.09 a |
stance phase [s] | 0.51 ± 0.03 | 0.53 ± 0.04 | 0.55 ± 0.05 a | 0.58 ± 0.07 a,b |
swing phase [s] | 0.45 ± 0.03 | 0.46 ± 0.03 | 0.46 ± 0.03 | 0.46 ± 0.05 |
MTC [cm] | 2.2 ± 0.6 | 2.2 ± 0.7 | 1.9 ± 0.5 | 2.1 ± 1.1 |
linear trend of mean gait parameter | ||||
walking speed slope | -0.002 ± 0.016 | -0.011 ± 0.014 | -0.011 ± 0.014 | -0.012 ± 0.014 a |
stride length slope | -0.000 ± 0.009 | -0.004 ± 0.007 | -0.004 ± 0.008 | -0.005 ± 0.008 |
stride time slope | 0.001 ± 0.004 | 0.005 ± 0.005 | 0.005 ± 0.005 | 0.007 ± 0.008 a |
stance phase slope | 0.000 ± 0.003 | 0.002 ± 0.003 | 0.003 ± 0.003 a | 0.005 ± 0.006 a |
swing phase slope | 0.001 ± 0.002 | 0.002 ± 0.002 | 0.001 ± 0.002 | 0.002 ± 0.002 |
MTC slope | -0.001 ± 0.000 | -0.001 ± 0.001 | -0.001 ± 0.000 | -0.000 ± 0.000 |
observer-rater tests | ||||
BBS | 56.0 ± 0.0 | 55.7 ± 1.2 | 55.0 ± 2.5 | 51.8 ± 4.8a,b,c |
TUG [s] | 4.5 ± 0.6 | 5.2 ± 1.0 | 5.8 ± 1.3a | 7.0 ± 1.6a,b,c |
fatigue | ||||
WEIMus | 2.2 ± 4.0 | 6.7 ± 7.1 | 9.6 ± 7.1 a | 17.7 ± 8.3 a,b,c |