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Fig. 3 | BMC Neurology

Fig. 3

From: Impairment of the visuospatial working memory in the patients with Parkinson’s Disease: an fMRI study

Fig. 3

fMRI analyses comparing the patients with PD and HC. The figure shows the results for the 0-back test (A), 2-back test (B) and subtracting the activated regions in the 0-back test from those in the 2-back test (C). The coloured regions indicate significantly lower brain activation in patients with PD, as compared with HC. The colour-bar represents t values as reference. All the images presented at P < 0.01 (uncorrected) with cluster size > 50 voxels in analysis. (A) The fMRI result during the 0-back test showed only a marginal difference in frontal lobe. (B) The result of the 2-back test showed the reduced activation in the bilateral dorsolateral prefrontal cortex, middle frontal gyrus, inferior parietal lobule, and superior parietal lobule. (C) The result of 2-back versus 0-back condition presented reduction of the activation in the bilateral prefrontal cortex, occipital cortex, and bilateral putamen

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