Fig. 4

Example spindle detections at age 9.6 years pre- and post- high dose diazepam treatment. Data is referenced the common average and spindle detections at each channel are highlighted. For detection, spindles are required to have regular oscillations that stand out from the background activity in the sigma band (9–15 Hz), not have an increase in theta activity (4-8 Hz) which can occur with epileptiform spikes, and last at least 0.5 s in duration [27]