Table 3 Basic information of patients with Becker muscular dystrophy
From: Serum creatinine as a biomarker for dystrophinopathy: a cross-sectional and longitudinal study
| Â | Â | Number (%) | Â | Total number (%) | Age (y) | ||
|---|---|---|---|---|---|---|---|
0–4 y | 5–9 y | 10–14 y | 15–19 y | 20–25 y | |||
Ethnic | 19 | 44 | 15 | 7 | 9 | 94 | Â |
 East Asian | 19 (100.00) | 44 (100.00) | 15 (100.00) | 7 (100.00) | 9 (100.00) | 94 (100.00) | 7 (5–12) |
Vignos scale | 16 (84.21) | 43 (97.73) | 15 (100.00) | 7 (100.00) | 8 (88.89) | 89 (94.68) | 7 (5–12) |
Brooke scale | 16 (84.21) | 43 (97.73) | 15 (100.00) | 7 (100.00) | 8 (88.89) | 89 (94.68) | 7 (5–12) |
complete GSGC scale | 9 (47.37) | 26 (59.09) | 5 (33.33) | 2 (28.57) | 2 (22.22) | 44 (46.81) | 6.5 (5–8.5) |
 Gait | 14 (73.68) | 30 (68.18) | 7 (46.67) | 3 (42.86) | 3 (33.33) | 57 (60.64) | 6 (5–9) |
 Time to walk 10 m | 1 (5.26) | 8 (18.18) | 0 (0.00) | 0 (100.00) | 2 (22.22) | 11 (11.70) | 7 (5–8.5) |
 Climbing stairs | 10 (52.63) | 27 (61.36) | 5 (33.33) | 2 (28.57) | 2 (22.22) | 46 (48.94) | 6.5 (5–8) |
 Time to climb four standard steps | 3 (15.79) | 8 (18.18) | 0 (0.00) | 0 (0.00) | 2 (22.22) | 13 (13.83) | 5 (5–7) |
 Gowers’ manoeuvre | 15 (78.95) | 31 (70.45) | 9 (60.00) | 4 (57.14) | 4 (44.44) | 63 (67.02) | 7 (5–10) |
 Time to stand up from ground | 12 (63.16) | 21 (47.73) | 5 (33.33) | 2 (28.57) | 3 (33.33) | 43 (45.74) | 7 (4–9) |
 Arising from a chair | 9 (47.37) | 26 (59.09) | 7 (46.67) | 2 (28.57) | 2 (22.22) | 46 (48.94) | 7 (5–9) |
 Time to arise from sitting | 2 (10.53) | 9 (20.45) | 2 (13.33) | 0 (0.00) | 2 (22.22) | 15 (15.96) | 7 (5–10.5) |
 Loss of ambulation | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) | – |
MRI in legs | 1 (5.26) | 4 (9.09) | 3 (20.00) | 0 (0.00) | 0 (0.00) | 8 (8.51) | 7.63 ± 4.00 |
Muscle biopsy | 2 (10.53) | 1 (2.27) | 1 (6.67) | 1 (14.29) | 1 (11.11) | 6 (6.38) | 10.33 ± 7.00 |
Glucocorticoid administration | Â | ||||||
 Oral administration | 0 (0.00) | 17 (38.64) | 6 (40.00) | 0 (0.00) | 2 (22.22) | 25 (26.60) | 8 (6–11) |
 None | 11 (57.89) | 26 (59.09) | 6 (40.00) | 1 (14.29) | 1 (11.11) | 45 (47.87) | 7 (5–8) |
 Unknown | 8 (42.11) | 1 (2.27) | 3 (20.00) | 0 (0.00) | 6 (66.67) | 18 (19.15) | 14 (3–19.5) |
Mutation analysis | 19 | 44 | 14 | 7 | 9 | 93 | 7 (5–12) |
 Deletion | 12 (63.16) | 32 (72.73) | 7 (50.00) | 4 (57.14) | 6 (66.67) | 61 (65.59) | 7 (5–10) |
 Duplication | 2 (10.53) | 3 (6.82) | 3 (21.43) | 0 (0.00) | 0 (0.00) | 8 (8.60) | 7.88 ± 3.68 |
 Point mutation | 5 (26.31) | 9 (20.45) | 4 (28.57) | 3 (42.86) | 3 (33.33) | 24 (25.81) | 10.10 ± 6.76 |