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Table 3 Demographic data of patients taking predominant sodium channel blocking antiseizure medications

From: Response to Sodium Channel blocking Antiseizure medications and coding polymorphisms of Sodium Channel genes in Taiwanese epilepsy patients

 

All (n = 82)

Response (n = 58)

Not seizure-free (n = 24)

p

Onset age (year)

17.5 (12.8–26.0)

15.0 (8.0–19.0)

19.0 (15.0–28.0)

0.020

Male

34 (41.5)

24 (41.4)

10 (41.7)

reference

Female

48 (58.5)

34 (58.6)

14 (58.3)

0.981

Seizure type

 Focal

51 (62.2)

34 (58.6)

17 (70.8)

0.382

 Generalized

17 (20.7)

12 (20.7)

5 (20.8)

 

 Unspecified

14 (17.1)

12 (20.7)

2 (8.3)

 

Etiology

 Structural

13 (15.9)

8 (13.8)

5 (20.8)

0.072

 CNS infection

4 (4.9)

3 (5.2)

1 (4.2)

 

 Genetic

1 (1.2)

0 (0.0)

1 (4.2)

 

 Autoimmune

2 (2.4)

0 (0.0)

2 (8.3)

 

 Unknown

62 (75.6)

47 (81.0)

15 (62.5)

 

Number of ASMs

 1

46 (56.1)

40 (69.0)

6 (25.0)

 

 2

23 (28.0)

13 (22.4)

10 (41.7)

 

 3

12 (14.6)

5 (8.6)

7 (29.2)

 

 4

0 (0.0)

0 (0.0)

0 (0.0)

 

 5

1 (1.2)

0 (0.0)

1 (4.2)

 

Concurrent ASMs

 Carbamazepine

29

21

8

 

 Clobazam

3

2

1

 

 Gabapentin

1

0

1

 

 Lacosamide

2

0

2

 

 Lamotrigine

34

24

10

 

 Levetiracetam

24

10

14

 

 Oxcarbazepine

10

6

4

 

 Perampanel

1

0

1

 

 Phenobarbital

1

0

1

 

 Phenytoin

27

18

9

 

 Vigabatrin

1

0

1

 
  1. Continuous variables were presented as median (interquartile range)
  2. Categorical variables were presented as n (%)
  3. Abbreviations: CNS central nervous system, ASM antiseizure medication