Gene | SNPs | Genotypes | Alleles | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Response (n = 58) | Not seizure-free (n = 24) |  | Response A:B; not seizure-free A:B | Odds ratio (95% CI) | P* | ||||||
A/B | AA | AB | BB | AA | AB | BB | p | |||||
SCN1A | rs121918808 | C/T | 57 | 1 | 0 | 24 | 0 | 0 | 1.0000 | 115:1; 48:0 | Â | 1.0000 |
 | rs200176684 | C/T | 57 | 0 | 1 | 24 | 0 | 0 | 1.0000 | 114:2; 48:0 |  | 0.5834 |
 | rs201985242 | G/C | 58 | 0 | 0 | 24 | 0 | 0 | 1.0000 | 116:0; 48:0 |  | 1.0000 |
SCN1B | rs55742440 | T/C | 40 | 17 | 1 | 12 | 8 | 4 | 0.0310 | 97:19; 32:16 | 0.392 (0.180–0.851) | 0.0159 |
 | rs3746255 | C/T | 57 | 1 | 0 | 22 | 2 | 0 | 0.2036 | 115:1; 46:2 | 0.2 (0.017–2.260) | 0.2052 |
 | rs67486287 | G/C | 41 | 16 | 1 | 17 | 5 | 2 | 0.3292 | 98:18; 39:9 | 0.796 (0.330–1.923) | 0.6101 |
 | rs67701503 | C/A | 41 | 16 | 1 | 17 | 5 | 2 | 0.3292 | 98:18; 39:9 | 0.796 (0.330–1.923) | 0.6101 |
 | rs2305748 | C/T | 41 | 16 | 1 | 17 | 5 | 2 | 0.3292 | 98:18; 39:9 | 0.796 (0.330–1.923) | 0.6101 |
 | rs369032304 | G/A | 58 | 0 | 0 | 24 | 0 | 0 | 1.0000 | 116:0; 48:0 |  | 1.0000 |
 | rs72558026 | G/A | 57 | 1 | 0 | 20 | 4 | 0 | 0.0241 | 115:1; 44:4 | 0.096 (0.010–0.880) | 0.0261 |
SCN2A | rs2060198 | T/A | 54 | 4 | 0 | 24 | 0 | 0 | 0.3158 | 112:4; 48:0 | Â | 0.3222 |
 | rs17183814 | G/A | 41 | 14 | 3 | 14 | 9 | 1 | 0.4452 | 96:20; 37:11 | 0.701 (0.306–1.603) | 0.5110 |
 | rs138497939 | A/C | 57 | 1 | 0 | 24 | 0 | 0 | 1.0000 | 115:1; 48:0 |  | 1.0000 |
 | rs185590667 | T/C | 57 | 1 | 0 | 24 | 0 | 0 | 1.0000 | 115:1; 48:0 |  | 1.0000 |
 | rs199925238 | G/A | 54 | 4 | 0 | 21 | 3 | 0 | 0.4418 | 112:4; 45:3 | 0.536 (0.115–2.490) | 0.6746 |
 | rs186154973 | G/A | 57 | 1 | 0 | 24 | 0 | 0 | 1.0000 | 115:1; 48:0 |  | 1.0000 |
SCN9A | rs9646771 | T/C | 39 | 12 | 7 | 14 | 5 | 5 | 0.5625 | 90:26; 33:15 | 0.636 (0.300–1.346) | 0.2351 |
 | rs3750904 | T/C | 44 | 11 | 3 | 18 | 6 | 0 | 0.6353 | 99:17; 42:6 | 1.202 (0.433–3.261) | 0.7184 |
 | rs199756028 | G/A | 57 | 1 | 0 | 24 | 0 | 0 | 1.0000 | 115:1; 48:0 |  | 1.0000 |
 | rs200613417 | A/T | 58 | 0 | 0 | 23 | 1 | 0 | 0.2926 | 116:0; 47:1 |  | 0.2927 |
 | rs200956485 | G/A | 57 | 1 | 0 | 24 | 0 | 0 | 1.0000 | 115:1; 48:0 |  | 1.0000 |