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Table 1 The clinical and demographical characteristics of patients before treatment(s) (for stroke)

From: Endovascular Thrombectomy preceded by intravenous Alteplase versus endovascular Thrombectomy alone in Han Chinese patients treated for acute ischemic stroke with large vessel occlusion: a single-center retrospective analysis

Parameters

Cohorts

Comparisons

EA cohort

ET cohort

Treatment(s)

Endovascular thrombectomy + intravenous alteplase intervention

Endovascular thrombectomy

Numbers of patients who underwent treatment

184

141

p-value

Age (years)

 Minimum

58

59

0.231

 Maximum

73

71

 Mean ± SD

64.12 ± 5.49

63.41 ± 5.01

Sex

 Male

103 (56)

89 (63)

0.212

 Female

81 (44)

52 (37)

The National Institutes of Health Stroke Scale score

 Minimum

6

6

0.441

 Maximum

22

22

 Median

14

14

 Mean ± SD

16.34 ± 4.60

13.94 ± 4.69

Previous ischemic stroke

21 (11)

19 (13)

0.612

History of atrial fibrillation

71 (39)

49 (35)

0.489

Type-2 diabetic

32 (17)

28 (20)

0.568

Hypertensive

101 (55)

82 (58)

0.574

Hypercholesterolemia

8 (4)

7 (5)

0.796

Peripheral artery disease

3 (2)

1 (1)

0.636

Smoking

 No smoker

147 (80)

108 (77)

0.768

 Previous smoker

35 (19)

31 (22)

 Current smoker

2 (1)

2 (1)

The modified Rankin scale score

 0

120 (65)

82 (58)

0.427

 1

45 (24)

41 (29)

 2

19 (10)

18 (13)

The Alberta Stroke Program Early Computed Tomography Score

8.15 ± 1.85

8.11 ± 1.86

0.847

Systolic blood pressure (mmHg)

145 ± 11

143 ± 12

0.119

Blood glucose (mg/ dL)

129 ± 11

127 ± 15

0.167

Reasons for stroke

 Cardio-embolism

79 (43)

61 (43)

0.973

 Intracranial atherosclerosis

15 (8)

13 (9)

 Ipsilateral extracranial internal carotid artery obstruction

21 (11)

17 (12)

 Unspecified

69 (38)

50 (35)

Intracranial artery occlusion location

 Intracranial internal carotid artery

61 (33)

41 (29)

0.681

 M1 segment of middle cerebral artery

95 (52)

75 (53)

 M2 segment of middle cerebral artery

28 (15)

25 (18)

  1. Constant variables are demonstrated as frequency (percentages) and continuous and ordinal variables are demonstrated as mean ± standard deviation (SD)
  2. Unpaired t-test (for continuous and ordinal variables) and Fischer exact test or the Chi-square test of Independence (for constant variables) were performed for statistical analysis
  3. Results were significant if p-value was < 0.05