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Fig. 1 | BMC Neurology

Fig. 1

From: Cell type-specific potential pathogenic genes and functional pathways in Alzheimer’s Disease

Fig. 1

Microglia. Overlapping differentially expressed genes (DEGs) and pathways in microglia from 3 studies. A Venn diagram showing overlapping DEGs detected in microglia. B List of overlapping DEGs at least in 2 studies. Heatmap colored by gene expression in each study (red: up-regulated, blue: down-regulated). C PPI network of overlapping DEGs. Significant modules are indicated in circle layout. Significance of hub genes is indicated by color; red to yellow means significance from high to low. D Top 20 significant gene ontology (GO) terms for overlapping DEGs. E Significant KEGG pathways of DEGs in microglia. Red circles show pathways generated using overlapping DEGs. In bubble charts, significance is indicated by color, and the gene number of DEGs is indicated by the size of a dot

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