From: Hemogram parameters can predict in-hospital mortality of patients with Myasthenic crisis
During mechanical ventilation | |||||
---|---|---|---|---|---|
Mortality | Survival | ||||
M_dMV (N = 26) | S_dMV (N = 139) | Crude p | OR (95%CI) | Adjusted p | |
Age at MC onset (years) | 66.73 ± 15 | 52.42 ± 18.14 | <0.001* | 1.039 (1.006-1.074) | 0.022* |
Sex | |||||
 Female / Male | 12 / 14 | 83 / 56 | 0.199 | ||
Underlying diseases [n (%)] | |||||
 Hypertension | 3 (11.5) | 36 (25.9) | 0.136 | ||
 Diabetes mellitus | 4 (15.4) | 24 (17.3) | 1.000 | ||
 Dyslipidemia | 0 (0) | 5 (3.6) | 1.000 | ||
 COPD | 0 (0) | 3 (2.2) | 1.000 | ||
 Liver cirrhosis | 4 (15.4) | 2 (1.4) | 0.006* | 6.19 (0.719-53.266) | 0.097 |
 CRF | 1 (3.8) | 5 (3.6) | 1.000 | ||
Medication for MG before admission [n (%)] | |||||
 Pyridostigmine only | 5 (19.2) | 24 (17.3) | 0.809 | ||
 DMT with or without pyridostigmine | 17 (65.4) | 85 (61.2) | 0.683 | ||
 Prednisolone monotherapy | 11 (64.7) | 50 (58.8) | 0.080 | ||
 Immunosuppressant monotherapy | 3 (17.6) | 4 (4.7) | |||
 Prednisolone + Immunosuppressant | 3 (17.6) | 31 (36.5) | |||
 PE / DFPP [n (%)] | 6 (23.1) | 88 (63.3) | 0.000* | 0.236 (0.077-0.728) | 0.012* |
Hemogram in 3 days before intubation | |||||
 Hb (g/dL) | 10.32 ± 2.7 | 12.66 ± 2.15 | <0.001* | ||
 Hb < 11 g/dL [n (%)] | 16 (61.5) | 30 (21.6) | <0.001* | 5.851 (2.003-17.092) | 0.001* |
 Platelet (x 109/L) | 140.88 ± 84.37 | 225.62 ± 106.56 | <0.001* | ||
 Platelet < 150 x 109/L [n (%)] | 13 (50) | 34 (24.5) | 0.008* | 1.045 (0.349-3.126) | 0.937 |
 WBC (x 109/L) | 16.83 ± 12.3 | 13.9 ± 7.7 | 0.250 | ||
 WBC≧25 x 109/L [n (%)] | 5 (19.2) | 9 (6.5) | 0.032* | 5.659 (1.28-25.023) | 0.022* |
 Neutrophil (%) | 79.88 ± 17.32 | 82.18 ± 12.31 | 0.415 | ||
 Lymphocyte (%) | 13.65 ± 15.99 | 12.03 ± 9.25 | 0.620 | ||
 NLR | 20.2 ± 22.59 | 14.66 ± 20.83 | 0.221 |