Skip to main content

Table 3 Comparison of the outcomes in MC patients after extubation

From: Hemogram parameters can predict in-hospital mortality of patients with Myasthenic crisis

 

After extubation

Mortality

Survival

  

M_aET (N = 11)

S_aET (N = 106)

Crude p

OR (95%CI)

Adjusted p

Age at MC onset (years)

66.27 ± 13.93

52.31 ± 17.51

0.012*

1.05 (0.997-1.104)

0.063

Sex

 Female / Male

6 / 5

63 / 43

0.754

  

Underlying diseases [n (%)]

 Hypertension

2 (18.2)

29 (27.4)

0.725

  

 Diabetes mellitus

3 (27.3)

19 (17.9)

0.431

  

 Dyslipidemia

1 (9.1)

3 (2.8)

0.330

  

 COPD

0 (0)

3 (2.8)

1.000

  

 Liver cirrhosis

1 (9.1)

1 (0.9)

0.180

  

 CRF

1 (9.1)

2 (1.9)

0.258

  

Acute comorbidity [n (%)]

 AMI

0 (0)

2 (1.9)

1.000

  

 AKI

3 (27.3)

4 (3.8)

0.018*

4.3 (0.65-28.457)

0.13

Medication for MG before admission [n (%)]

 Pyridostigmine only

5 (45.5)

15 (14.2)

0.009*

5.459 (1.17-25.472)

0.031*

 DMT with or without pyridostigmine

4 (36.4)

63 (59.4)

0.201

  

 Prednisolone monotherapy

3 (75)

34 (54)

0.050

  

 Immunosuppressant monotherapy

1 (25)

2 (3.2)

   

 Prednisolone + Immunosuppressant

0 (0)

27 (42.9)

   

 PE / DFPP [n (%)]

5 (45.5)

65 (61.3)

0.307

  

Hemogram in 3 days before extubation

 Hb (g/dL)

10.24 ± 1.14

11.81 ± 1.83

0.006*

  

 Hb < 11 g/dL [n (%)]

9 (81.8)

35 (33)

0.002*

8.452 (1.455-49.089)

0.017*

 Platelet (x 109/L)

202 ± 58.62

237.29 ± 112.39

0.308

  

 Platelet < 150 x 109/L [n (%)]

2 (18.2)

22 (20.8)

1.000

  

 WBC (x 109/L)

9.6 ± 2.93

13.75 ± 7.73

0.081

  

 WBC≧25 x 109/L [n (%)]

0 (0)

8 (7.5)

1.000

  

 Neutrophil (%)

71.98 ± 25.56

81.86 ± 11.41

0.232

  

 Lymphocyte (%)

14.74 ± 13.53

12.12 ± 8.14

0.543

  

 NLR

11.36 ± 11.11

13.73 ± 23

0.736

  

 Reintubation within 3 days

3 (27.3)

10 (9.4)

0.105

  

 Mechanical ventilation more than 14 days

2 (18.2)

4 (3.8)

0.098

  
  1. ѱ Abbreviations: AKI Acute kidney injury, AMI Acute myocardial infarction, COPD Chronic obstructive pulmonary disease, CRF Chronic renal failure, DMT Disease modified therapy, Hb Hemoglobin, MC Myasthenic crisis, M_aET Mortality after extubation, NLR Neutrophil-lymphocyte ratio, S_aET Survival after extubation, PE / DFPP Plasma exchange or double-filtration plasmapheresis, WBC White blood count