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Fig. 4 | BMC Neurology

Fig. 4

From: Differences in peripheral neuropathy in xeroderma pigmentosum complementation groups A and D as evaluated by nerve conduction studies

Fig. 4

Nerve and muscle pathology of XP-A and XP-D patients. A XPA (XP5 - XP12BE) patient median nerve - H&E, 20x, normal nerve architecture on longitudinal section. B XP-A (XP5 - XP12BE) patient psoas muscle – H&E, 20x, marked variation in myofiber size characterized by the presence of many rounded and angular atrophic fibers, approaching panfascicular atrophy in some areas with fatty infiltration. Numerous pyknotic nuclear clumps are also present. C XP-D patient nerve from arm but not specified – H&E, 10x, normal nerve architecture on cross-section. D XP-D patient psoas muscle – H&E, 20x, mild variation of muscle fiber size with occasional small-sized angulated fibers. (Modified from JP Lai, et al. 2013, permission by Dr. K. Kraemer)

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BMC Neurology

ISSN: 1471-2377

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