Table 1 Baseline tumour and patient characteristics; normally distributed variables shown as mean ± standard deviation, non-normally distributed as median (interquartile range); KPSS (Karnofsky Performance Status Scale)
Demographic data | |
|---|---|
Age | 67.4 ± 13.4 years, range 21–90 years |
Female | 58/123 (47.2%) |
Male | 65/123 (52.85%) |
Surgical data & tumor burden | |
Biopsy | 48/123 (39%) |
Median preoperative tumor volume | 26.3 ± 30.9 cm3 (IR 8.1–51.7 cm3) |
Median postoperative tumor volume | 26.3 ± 30.9 cm3 (IR 8.1–51.7 cm3) |
Resection | 75/123 (61%) |
Median preoperative tumor volume | 35.2 ± 31.3 cm3 (IR 19.7–65.3 cm3) |
Median postoperative tumor volume | 0.5 ± 2.8 cm3 (IR 0–2.3 cm3) |
Karnofsky Performance Status Scale | |
Median preoperative KPSS | 60% (20–60%) |
Median postoperative KPSS | 50% (0–80%) |
Overall survival | |
Median overall survival | 5 months (95% CI 3.0–4.0) |
Median overall survival after biopsy | 3 months (95% CI 2.0–4.0) |
Median overall survival after surgery | 8 months (95% CI 3.1–12.9) |
MGMT-methylation status | |
MGMT- methylation status available | 81/123 (65.9%) |
MGMT-methylated | 26/81 (32.1%) |
MGMT-unmethylated | 55/81 (67.9%) |