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Table 3 Adjusted logistic regression models for association of NLR with the relapse of NMOSD

From: Association of neutrophil-to-lymphocyte ratio (NLR) with the prognosis of first attack neuromyelitis optica spectrum disorder (NMOSD): a retrospective cohort study

Variables

Basic model

Adjust-I model

Adjust-II model

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

NLR

1.35(1.14, 1.59)

< 0.001

1.33 (1.21, 1.57)

< 0.001

1.33(1.11, 1.59)

0.002

PLR

1.00(0.99, 1.01)

0.213

1.00 (0.99, 1.02)

0.251

1.00 (0.99, 1.01)

0.206

LMR

0.98(0.91, 1.05)

0.586

0.98 (0.91, 1.05)

0.591

0.99 (0.92, 1.07)

0.836

Sex

  

0.86 (0.40, 1.86)

0.703

0.93 (0.42, 2.06)

0.863

Age

  

1.00 (0.98, 1.02)

0.607

1.00 (0.98, 1.02)

0.645

LETM

  

0.97 (0.46, 2.06)

0.945

1.00 (0.47, 2.17)

0.981

Anti-AQP4 antibodies

  

0.85 (0.41, 1.76)

0.667

0.84 (0.40, 1.76)

0.649

Initial EDSS

  

1.06 (0.9, 1.27)

0.447

1.06 (0.88, 1.28)

0.526

Hypertension

    

0.60 (0.22, 1.66)

0.328

Diabetes

    

2.09 (0.46, 9.53)

0.343

Corticosteroids

    

1.65 (035, 7.72)

0.528

Immunoglobulins

    

1.34 (0.43, 4.17)

0.611

Immunosuppressants

    

0.97 (0.49, 1.94)

0.932

DMT

    

1.44 (0.54,3.87)

0.466

  1. EDSS Extended disability status scale, LMR Lymphocyte-to-monocyte technical ratio, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, LETM longitudinally extensive transverse myelitis, AQP4 aquaporin-4, DMT disease-modifying treatment started during the follow-up