Association of neutrophil-to-lymphocyte ratio (NLR) with the prognosis of first attack neuromyelitis optica spectrum disorder (NMOSD): a retrospective cohort study

Table 4 Adjusted logistic regression models for the association of NLR with poor recovery in patients with NMOSD

Variables	Basic model		Adjust-I model		Adjust-II model
Variables	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
NLR	1.24 (1.01, 1.42)	0.003	1.23 (1.06, 1.43)	0.005	1.23 (1.06, 1.43)	0.007
PLR	1.00 (0.99, 1.01)	0.359	1.00 (0.99, 1.01)	0.416	1.00 (0.99, 1.01)	0.360
LMR	1.04 (0.95, 1.14)	0.381	1.04 (0.95, 1.15)	0.393	1.05 (0.95, 1.16)	0.370
Sex			0.82 (0.39, 1.75)	0.61	0.84 (0.39, 1.85)	0.669
Age			1.00 (0.98, 1.02)	0.914	1.00 (0.98, 1.02)	0.887
LETM			1.36 (0.65, 2.84)	0.412	1.28 (0.60, 2.70)	0.524
Anti-AQP4 antibodies			0.99 (0.49, 2.00)	0.985	0.98 (0. 47, 1.99)	0.932
Initial EDSS			1.14 (0.96, 1.35)	0.12	1.14 (0.95, 1.36)	0.167
Hypertension					0.58 (0.22, 1.52)	0.269
Diabetes					0.58 (0.13, 1.87)	0.294
Corticosteroids					1.30 (0.27, 6.12)	0.763
Immunoglobulins					1.83 (0.57, 5.90)	0.312
Immunosuppressants					0.93 (0.47, 1.83)	0.822
DMT					1.41 (0.54, 3.72)	0.487

EDSS Extended disability status scale, LMR Lymphocyte-to-monocyte technical ratio, NLR Neutrophil-to-lymphocyte ratio, PLR Platelet-to-lymphocyte ratio, LETM longitudinally extensive transverse myelitis, AQP4 aquaporin-4, DMT disease-modifying treatment started during the follow-up

ISSN: 1471-2377