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Table 1 Baseline characteristics of study patients

From: Early argatroban and antiplatelet combination therapy in acute non-lacunar single subcortical infarct associated with mild intracranial atherosclerosis

Variable

DAPT group (n = 168)

Argatroban group (n = 136)

P Value

Demographics

 Age, mean (SD), y

62 ± 7.8

63 ± 6.4

0.17

 Male, no. (%)

96(57.1)

73 (59.3)

0.34

Medical history

 Hypertension, no. (%)

91(54.1)

71(52.2)

0.73

 Diabetes mellitus, no. (%)

86(51.1)

76(55.8)

0.41

 Hyperlipidemia, no. (%)

93(55.3)

65(47.7)

0.88

 Current smoker, no. (%)

70(41.6)

62(45.5)

0.49

 History of stroke, no. (%)

22(13.0)

20(14.7)

0.62

 History of coronary artery disease, no. (%)

65(38.6)

47(34.5)

0.45

Laboratory measures

 Glucose, mean (SD), mmol/L

7.2 (2.6)

7.4 (3.1)

0.61

 Hematocrit, mean (SD)

0.41(0.16)

0.43(0.24)

0.68

 Fibrinogen, mean (SD), g/l

4.3(1.5)

4.0(1.0)

0.44

 WBC count, mean (SD), 109/L

7.6(2.5)

7.8(2.2)

0.63

 BUN, mean (SD), mmol/L

4.6(1.4)

4.7(1.6)

0.72

 Cr, mean (SD), mmol/L

66(8.2)

64(6.4)

0.63

Clinical characteristics

 SBP, Median (IQR), mmHg

159 (125–168)

140 (121–151)

0.03

 Initial diameter, mean (SD), mm

17.6 ± 2.1

17.8 ± 2.1

0.29

 Presence of microbleeds, no. (%)

20(11.9)

16(13.0)

0.59

 Plaques in superior side, no. (%)

25/46(54.3)

20/32(62.5)

0.49

 Baseline NIHSS score, Median (IQR)

4 (3–7)

4 (3–6)

0.47

Medicine

 Stain, no. (%)

21(12.5)

19(13.9)

0.82

 Antihypertensive, no. (%)

87(51.8)

59(43.4)

0.56

  1. Abbreviations: SD standard deviation, IQR interquartile range, NIHSS National Institutes of Health Stroke Scale, WBC white blood cell, BUN blood urea nitrogen, Cr creatinine, SBP systolic pressure