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Table 1 Multivariate Cox regression analysis of influence of factors on survival in bulbar onset ALS patients

From: Disease duration of progression is helpful in identifying isolated bulbar palsy of amyotrophic lateral sclerosis

Variable

HR

95% CI

P

Gender

 Famale

1.000

  

 Male

0.721

0.470–1.106

0.134

 Onset age (year)

1.018

0.998–1.038

0.074

 Duration (month)

0.912

0.886–0.939

< 0.001

 ALSFRS-R

0.986

0.955–1.018

0.380

Use of riluzole

 No

1.000

  

 Yes

1.170

0.755–1.812

0.483

Use of NIV

 No

1.000

  

 Yes

0.951

0.577–1.568

0.844

  1. ALS amyotrophic lateral sclerosis, Duration duration from bulbar onset to first significant limb involvement, ALSFRS-R Revised ALS Functional Rating Scale, NIV noninvasive ventilation