From: Triglyceride glucose index influences platelet reactivity in acute ischemic stroke patients
Characteristics | Q1 (< 2.02) (n = 250) | Q2 (2.02–2.27) (n = 251) | Q3 (2.27–2.52) (n = 251) | Q4 (≥2.52) (n = 250) | P Value |
---|---|---|---|---|---|
Age, y | 57.0 [50.0–65.0] | 57.0 [50.0–65.0] | 58.0 [50.0–65.0] | 58.0 [52.0–64.3] | 0.737 |
Male, n (%) | 207 (82.8) | 183 (72.9) | 170 (67.7) | 166 (66.4) | < 0.001 |
Smoking, n (%) | 140 (56.0) | 126 (50.2) | 112 (44.6) | 113 (45.2) | 0.038 |
Alcohol intake, n (%) | 117 (46.8) | 106 (42.2) | 95 (37.8) | 95 (38.0) | 0.135 |
Medical history, n (%) | |||||
 History of stroke/TIA | 49 (19.6) | 47 (18.7) | 39 (15.5) | 55 (22.0) | 0.322 |
 Hypertension | 173 (69.2) | 158 (62.9) | 177 (70.5) | 170 (68.0) | 0.288 |
 Diabetes mellitus | 64 (25.6) | 55 (21.9) | 70 (27.9) | 149 (59.6) | < 0.001 |
 Hyperlipidemia | 21 (8.4) | 27 (10.8) | 27 (10.8) | 37 (14.8) | 0.149 |
 Coronary heart disease | 23 (9.2) | 16 (6.4) | 22 (8.8) | 26 (10.4) | 0.440 |
Biochemical indexes | |||||
 Triglyceride (mmol/L) | 2.5 [2.2–2.9] | 3.3 [3.1–3.7] | 4.0 [3.5–4.3] | 4.6 [3.9–5.2] | < 0.001 |
 Total cholesterol (mmol/L) | 1.0 [0.8–1.3] | 1.2 [0.9–1.7] | 1.4 [1.1–1.9] | 1.6 [1.1–2.3] | < 0.001 |
 HDL-C (mmol/L) | 0.9 [0.7–1.0] | 0.9 [0.8–1.1] | 0.9 [0.8–1.1] | 1.0 [0.8–1.1] | < 0.001 |
 LDL-C (mmol/L) | 1.3 [1.1–1.6] | 2.0 [1.7–2.3] | 2.5 [2.1–2.9] | 2.9 [2.3–3.6] | < 0.001 |
 Creatinine (μmol/L) | 74.0 [65.0–87.0] | 71.0 [61.0–83.0] | 72.0 [62.0–83.0] | 71.0 [59.0–84.0] | 0.041 |
 eGFR (mL/min/1.73m2) | 94.8 [80.6–105] | 96.1 [84.9–104] | 92.3 [83.1–103] | 95.4 [81.4–103] | 0.580 |
 Platelet count (× 109/L) | 211 [169–247] | 209 [175–258] | 211 [178–250] | 220 [184–259] | 0.039 |
 PDW (fL) | 13.5 [11.9–15.1] | 13.1 [11.7–14.9] | 13.3 [11.9–15.3] | 13.2 [11.7–14.9] | 0.617 |
 P-LCR (%) | 33.8 [28.2–40.4] | 32.4 [27.0–39.7] | 32.0 [26.6–39.7] | 32.9 [27.0–38.5] | 0.210 |
 Fasting glucose (mmol/L) | 4.9 [4.6–5.3] | 5.1 [4.8–5.5] | 5.4 [5.1–6.1] | 7.1 [5.8–10.0] | < 0.001 |
 HbA1c (%) | 5.7 [5.5–6.2] | 5.7 [5.5–6.1] | 5.8 [5.5–6.3] | 6.7 [5.8–10.3] | < 0.001 |