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Table 1 Patient baseline characteristics according to TyG index quartiles

From: Triglyceride glucose index influences platelet reactivity in acute ischemic stroke patients

Characteristics Q1 (< 2.02) (n = 250) Q2 (2.02–2.27) (n = 251) Q3 (2.27–2.52) (n = 251) Q4 (≥2.52) (n = 250) P Value
Age, y 57.0 [50.0–65.0] 57.0 [50.0–65.0] 58.0 [50.0–65.0] 58.0 [52.0–64.3] 0.737
Male, n (%) 207 (82.8) 183 (72.9) 170 (67.7) 166 (66.4) < 0.001
Smoking, n (%) 140 (56.0) 126 (50.2) 112 (44.6) 113 (45.2) 0.038
Alcohol intake, n (%) 117 (46.8) 106 (42.2) 95 (37.8) 95 (38.0) 0.135
Medical history, n (%)
 History of stroke/TIA 49 (19.6) 47 (18.7) 39 (15.5) 55 (22.0) 0.322
 Hypertension 173 (69.2) 158 (62.9) 177 (70.5) 170 (68.0) 0.288
 Diabetes mellitus 64 (25.6) 55 (21.9) 70 (27.9) 149 (59.6) < 0.001
 Hyperlipidemia 21 (8.4) 27 (10.8) 27 (10.8) 37 (14.8) 0.149
 Coronary heart disease 23 (9.2) 16 (6.4) 22 (8.8) 26 (10.4) 0.440
Biochemical indexes
 Triglyceride (mmol/L) 2.5 [2.2–2.9] 3.3 [3.1–3.7] 4.0 [3.5–4.3] 4.6 [3.9–5.2] < 0.001
 Total cholesterol (mmol/L) 1.0 [0.8–1.3] 1.2 [0.9–1.7] 1.4 [1.1–1.9] 1.6 [1.1–2.3] < 0.001
 HDL-C (mmol/L) 0.9 [0.7–1.0] 0.9 [0.8–1.1] 0.9 [0.8–1.1] 1.0 [0.8–1.1] < 0.001
 LDL-C (mmol/L) 1.3 [1.1–1.6] 2.0 [1.7–2.3] 2.5 [2.1–2.9] 2.9 [2.3–3.6] < 0.001
 Creatinine (μmol/L) 74.0 [65.0–87.0] 71.0 [61.0–83.0] 72.0 [62.0–83.0] 71.0 [59.0–84.0] 0.041
 eGFR (mL/min/1.73m2) 94.8 [80.6–105] 96.1 [84.9–104] 92.3 [83.1–103] 95.4 [81.4–103] 0.580
 Platelet count (× 109/L) 211 [169–247] 209 [175–258] 211 [178–250] 220 [184–259] 0.039
 PDW (fL) 13.5 [11.9–15.1] 13.1 [11.7–14.9] 13.3 [11.9–15.3] 13.2 [11.7–14.9] 0.617
 P-LCR (%) 33.8 [28.2–40.4] 32.4 [27.0–39.7] 32.0 [26.6–39.7] 32.9 [27.0–38.5] 0.210
 Fasting glucose (mmol/L) 4.9 [4.6–5.3] 5.1 [4.8–5.5] 5.4 [5.1–6.1] 7.1 [5.8–10.0] < 0.001
 HbA1c (%) 5.7 [5.5–6.2] 5.7 [5.5–6.1] 5.8 [5.5–6.3] 6.7 [5.8–10.3] < 0.001
  1. Data given as n (%) or median [interquartile range]
  2. Abbreviations: TyG index triglyceride glucose index, Q1–Q4 TyG index quartiles, TIA transient ischemic attack, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR glomerular filtration rate, PDW platelet distribution width, P-LCR platelet large cell ratio, HbAc1 glycosylated hemoglobin A1c