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Table 1 Patient baseline characteristics according to TyG index quartiles

From: Triglyceride glucose index influences platelet reactivity in acute ischemic stroke patients

Characteristics

Q1 (< 2.02) (n = 250)

Q2 (2.02–2.27) (n = 251)

Q3 (2.27–2.52) (n = 251)

Q4 (≥2.52) (n = 250)

P Value

Age, y

57.0 [50.0–65.0]

57.0 [50.0–65.0]

58.0 [50.0–65.0]

58.0 [52.0–64.3]

0.737

Male, n (%)

207 (82.8)

183 (72.9)

170 (67.7)

166 (66.4)

< 0.001

Smoking, n (%)

140 (56.0)

126 (50.2)

112 (44.6)

113 (45.2)

0.038

Alcohol intake, n (%)

117 (46.8)

106 (42.2)

95 (37.8)

95 (38.0)

0.135

Medical history, n (%)

 History of stroke/TIA

49 (19.6)

47 (18.7)

39 (15.5)

55 (22.0)

0.322

 Hypertension

173 (69.2)

158 (62.9)

177 (70.5)

170 (68.0)

0.288

 Diabetes mellitus

64 (25.6)

55 (21.9)

70 (27.9)

149 (59.6)

< 0.001

 Hyperlipidemia

21 (8.4)

27 (10.8)

27 (10.8)

37 (14.8)

0.149

 Coronary heart disease

23 (9.2)

16 (6.4)

22 (8.8)

26 (10.4)

0.440

Biochemical indexes

 Triglyceride (mmol/L)

2.5 [2.2–2.9]

3.3 [3.1–3.7]

4.0 [3.5–4.3]

4.6 [3.9–5.2]

< 0.001

 Total cholesterol (mmol/L)

1.0 [0.8–1.3]

1.2 [0.9–1.7]

1.4 [1.1–1.9]

1.6 [1.1–2.3]

< 0.001

 HDL-C (mmol/L)

0.9 [0.7–1.0]

0.9 [0.8–1.1]

0.9 [0.8–1.1]

1.0 [0.8–1.1]

< 0.001

 LDL-C (mmol/L)

1.3 [1.1–1.6]

2.0 [1.7–2.3]

2.5 [2.1–2.9]

2.9 [2.3–3.6]

< 0.001

 Creatinine (μmol/L)

74.0 [65.0–87.0]

71.0 [61.0–83.0]

72.0 [62.0–83.0]

71.0 [59.0–84.0]

0.041

 eGFR (mL/min/1.73m2)

94.8 [80.6–105]

96.1 [84.9–104]

92.3 [83.1–103]

95.4 [81.4–103]

0.580

 Platelet count (× 109/L)

211 [169–247]

209 [175–258]

211 [178–250]

220 [184–259]

0.039

 PDW (fL)

13.5 [11.9–15.1]

13.1 [11.7–14.9]

13.3 [11.9–15.3]

13.2 [11.7–14.9]

0.617

 P-LCR (%)

33.8 [28.2–40.4]

32.4 [27.0–39.7]

32.0 [26.6–39.7]

32.9 [27.0–38.5]

0.210

 Fasting glucose (mmol/L)

4.9 [4.6–5.3]

5.1 [4.8–5.5]

5.4 [5.1–6.1]

7.1 [5.8–10.0]

< 0.001

 HbA1c (%)

5.7 [5.5–6.2]

5.7 [5.5–6.1]

5.8 [5.5–6.3]

6.7 [5.8–10.3]

< 0.001

  1. Data given as n (%) or median [interquartile range]
  2. Abbreviations: TyG index triglyceride glucose index, Q1–Q4 TyG index quartiles, TIA transient ischemic attack, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, eGFR glomerular filtration rate, PDW platelet distribution width, P-LCR platelet large cell ratio, HbAc1 glycosylated hemoglobin A1c