| Amantadine (n = 31) | ST (n = 127) | P value |
---|---|---|---|
Age (years) | |||
 Mean ± SD | 70.68 ± 11.42 | 65.45 ± 15.32 | 0.077* |
 Median (range) | 76 (46–87) | 68 (18–94) | 0.061†|
Female, n (%) | 17 (54.83) | 69 (54.33) | 0.959‡ |
Time from onset (hours), median (range) | 2 (1–24) | 10 (1–24) | < 0.001†|
NIHSS score on admission | 21.71 ± 4.76 | 17.49 ± 5.84 | < 0.001* |
GCS score on adimission | 9.35 ± 1.72 | 10.17 ± 3.06 | 0.158* |
SBP on admission (mm Hg) | 150.45 ± 20.48 | 140.17 ± 26.96 | 0.056* |
DBP on admission (mm Hg) | 87.71 ± 14.95 | 82.87 ± 16.84 | 0.145* |
Serum glucose on admission (mmol/L) | 7.72 ± 4.49 | 7.88 ± 3.25 | 0.822* |
Risk factors, n (%) | |||
 Hypertension | 12 (38.71) | 66 (51.97) | 0.186‡ |
 Diabetes mellitus | 6 (19.35) | 27 (21.26) | 0.815‡ |
 Dyslipidemia | 6 (19.35) | 20 (15.75) | 0.627‡ |
 Coronary heart disease | 8 (25.81) | 21 (16.54) | 0.232‡ |
 Atrial fibrillation | 22 (70.97) | 70 (55.12) | 0.109‡ |
 Rheumatic heart disease | 5 (16.13) | 35 (27.56) | 0.189‡ |
 Current smoking | 10 (32.26) | 26 (20.47) | 0.161‡ |
 Alcohol consumption | 3 (9.68) | 19 (14.96) | 0.446 ‡ |
 Previous all strokes/TIA | 9 (29.03) | 26 (20.47) | 0.304‡ |
 Previous IS | 8 (25.81) | 18 (14.17) | 0.117‡ |
 Previous ICH | 1 (3.23) | 4 (3.15) | 0.983‡ |
 Previous TIA | 0 (0) | 4 (3.15) | 0.716‡ |
Stroke in dominant hemisphere, n (%) | 21 (67.74) | 58 (45.67) | 0.028‡ |
TOAST classification, n (%) |  |  | 0.572‡ |
 Large-artery atherosclerosis | 5 (16.13) | 32 (25.20) |  |
 Cardio-embolism | 23 (74.19) | 77 (60.63) |  |
 Other determined etiology | 1 (3.23) | 7 (5.51) |  |
 Undetermined etiology | 2 (6.45) | 11 (8.66) |  |