Table 2 Baseline characteristics of LHI patients after PSM
|  | Amantadine (n = 27) | ST (n = 45) | P value |
|---|---|---|---|
Age (years) | |||
 Mean ± SD | 69.89 ± 11.56 | 65.73 ± 15.77 | 0.238* |
 Median (range) | 76 (46–82) | 69 (15–93) | 0.264†|
Female, n (%) | 14 (51.85) | 24 (53.33) | 0.903‡ |
Time from onset (hours), median (range) | 3 (1–24) | 6 (1–24) | 0.074†|
NIHSS score on admission | 21.22 ± 4.90 | 20.64 ± 5.65 | 0.661* |
GCS score on adimission | 9.52 ± 1.76 | 8.51 ± 2.85 | 0.103* |
SBP on admission (mm Hg) | 150.11 ± 26.79 | 145.04 ± 30.72 | 0.480* |
DBP on admission (mm Hg) | 87.78 ± 15.98 | 86.42 ± 18.49 | 0.753* |
Serum glucose on admission (mmol/L) | 7.15 ± 2.20 | 8.39 ± 3.06 | 0.070* |
Risk factors, n (%) | |||
 Hypertension | 10 (37.04) | 25 (55.56) | 0.128‡ |
 Diabetes mellitus | 5 (16.13) | 15 (33.33) | 0.174‡ |
 Dyslipidemia | 6 (22.22) | 8 (17.78) | 0.645‡ |
 Coronary heart disease | 6 (22.22) | 7 (14.89) | 0.476‡ |
 Atrial fibrillation | 20 (74.07) | 24 (53.33) | 0.081‡ |
 Rheumatic heart disease | 4 (14.81) | 11 (24.44) | 0.330‡ |
 Current smoking | 9 (33.33) | 10 (22.22) | 0.300‡ |
 Alcohol consumption | 3 (11.11) | 8 (17.78) | 0.447 ‡ |
 Previous all strokes/TIA | 9 (33.33) | 11 (24.44) | 0.415‡ |
 Previous IS | 8 (29.63) | 8 (17.78) | 0.242‡ |
 Previous ICH | 1 (3.70) | 3 (6.67) | 0.595‡ |
 Previous TIA | 0 (0) | 0 (0) | – |
Stroke in dominant hemisphere, n(%) | 17 (62.96) | 27 (60.00) | 0.803‡ |
TOAST classification, n(%) |  |  | 0.621‡ |
 Large-artery atherosclerosis | 5 (18.52) | 8 (17.78) |  |
 Cardio-embolism | 20 (74.07) | 29 (64.44) |  |
 Other determined etiology | 1 (3.70) | 3 (6.67) |  |
 Undetermined etiology | 1 (3.70) | 5 (11.11) |  |