Table 3 In-hospital treatment, stroke-related complication and outcomes of LHI patients before and after PSM
Variables | Unmatched | PS-matched | ||||
|---|---|---|---|---|---|---|
Amantadine (n = 31) | ST (n = 127) | P value | Amantadine (n = 27) | ST (n = 45) | P value | |
Treatments, n (%) | ||||||
 Thrombolysis | 2 (6.45) | 4 (3.15) | 0.735 | 1 (3.70) | 3 (6.67) | 1.000 |
 Mechanical ventilation | 1 (3.23) | 6 (4.72) | 1.000 | 1 (3.70) | 5 (11.11) | 0.509 |
 Osmotic agents | 29 (93.55) | 110 (86.61) | 0.450 | 26 (96.30) | 42 (93.33) | 1.000 |
Complications, n (%) | ||||||
 Brain edema | 29 (93.55) | 40 (31.50) | <0.001 | 26 (96.30) | 41 (91.11) | 0.720 |
 Hemorrhagic transformation | 14 (45.16) | 31 (24.41) | 0.022 | 13 (48.15) | 13 (28.89) | 0.100 |
 Seizures | 4 (12.90) | 11 (8.66) | 0.703 | 4 (14.81) | 7 (15.56) | 1.000 |
 Pneumonia | 26 (83.87) | 81 (63.78) | 0.032 | 23 (85.19) | 42 (93.33) | 0.472 |
 Gastrointestinal bleeding | 6 (19.35) | 22 (17.32) | 0.791 | 6 (22.22) | 6 (13.33) | 0.514 |
 Acute renal failure | 7 (22.58) | 15 (11.81) | 0.206 | 6 (22.22) | 8 (17.78) | 0.645 |
Outcomes, n (%) | ||||||
 In-hospital death | 3 (9.68) | 27 (21.26) | 0.132 | 2 (7.41) | 14 (31.11) | 0.019 |
 3-month mortality | 9 (29.03) | 51 (40.16) | 0.228 | 7 (25.93) | 25 (55.56) | 0.008 |
 3-month unfavorable outcome | 19 (61.29) | 74 (58.27) | 0.832 | 16 (59.26) | 32 (71.11) | 0.184 |