Fig. 4
From: The protective impact of education on brain structure and function in Alzheimer’s disease
Effect of years of education on AD-related neuroimaging biomarkers, stratified by severity of AD: linear regression analysis. The y axis corresponds to the standardized residuals of GMV, ReHo, and FC values of ROI after adjustment for age, sex, MMSE and TIV or head motion parameters. The x axis corresponds to education years. CDR1 corresponds to a mild form, CDR2 to a moderate form, and CDR3 to a severe form of the disease, aMCI corresponds to preclinical stage of AD. Abbreviations: dACC, dorsal anterior cingulate cortex; GMV, gray matter volume; ReHo, Regional Homogeneity; aITC, anterior part of inferior temporal cortex; pITC, posterior part of inferior temporal cortex; MFC, mid frontal cortex; SFC, superior frontal cortex; rsFC, resting-state functional connectivity; AD, Alzheimer’s disease; aMCI, amnestic mild cognitive impairment; CDR, Clinical Dementia Rating