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Table 2 Study and patient characteristics – medication overuse headache among triptan users

From: The burden of medication overuse headache and patterns of switching and discontinuation among triptan users: a systematic literature review

Citation

Country (Study period)

Study type

Sample (MOH care setting, treatment)

n, MOH

% previous history migraine

Headache criteria

MHD

Mean age, yrs

% female

Benz et al., 2017 [42]

Switzerland (2012, 2014)

Single center cross-sectional, survey

Inpatient and outpatient, withdrawal of acute medication, prophylaxis

51

90.0

ICHD-II beta

NR

47.3

72.5

Chagas, 2015 [43]

Brazil (2009, 2010)

Single center prospective, survey

Outpatient, NR

29

100

ICHD-II

NR

44.2

82.8

Creac’h et al., 2009 [44]

France (2004, 2006)

Multicenter cross-sectional, survey

Inpatient, withdrawal of acute medication, prophylaxis; all overused triptans

163

99.0

ICHD-II

26.0

50.0

85.0

de Rijk et al., 2018 [45]

France (2006, 2015)

Single center, chart review

Inpatient, withdrawal of acute medication; > 65 years

79

100

ICHD-II beta

NR

69.5

79.1

Grande et al., 2011 [46]

Norway (2005, 2008)

Single center prospective, survey

Inpatient, education about medication overuse, prophylaxis

109

8.0

ICHD-II

22.0

37.5

30.3

Imai et al., 2007 [47]

Japan (NR)

Single center chart review

Inpatient and outpatient, withdrawal of acute medication

47

90.0

ICHD-II

NR

NR

NR

Katsarava et al., 2003a [48]

Germany (NR)

Single center prospective cohort

Outpatient, withdrawal of acute medication

96

71.0

ICHD-I

NR

43.0

81.0

Kluonaitis et al., 2017 [49]

Lithuania (2015, 2016)

Single center chart review

Outpatient, likely withdrawal of acute medication, patients on prophylactic medication were excluded

87

67.0

ICHD-II beta

24.1

43.8

90.8

Lake et al., 2009 [50]

US and Canada (NR)

Single center chart review

Inpatient, withdrawal from acute mediation, prophylaxis, cognitive-behavioral therapy

158

85.0

ICHD-II

NR

40.0

79.4

Limmroth et al., 2002a [51]

Germany (NR)

Single center prospective cohort

Outpatient, withdrawal of acute medication

96

71.0

ICHD-I

NR

43.0

81.0

Radat et al., 2005 [52]

France (NR)

Single center cross-sectional, survey

Inpatient, withdrawal of acute medication

41

100

ICHD-II

27.0

NR

NR

Zeeberg et al., 2006 [53]

Denmark (2002, 2003)

Single center prospective cohort

Outpatient, withdrawal of acute medication

216

53.0

ICHD-II

17.0

48.0

73.0

Zidverc-Trajkovic et al, 2007 [54]

Serbia (2000, 2005)

Single center prospective cohort

Inpatient, prophylaxis

240

67.1

ICHD-II

24.0

41.5

75.8

  1. Abbreviations: ICHD The International Classification of Headache Disorders, MOH Medication overuse headache, MHD Monthly headache days, NR Not reported, US United States, Yrs Years
  2. aSame patient population, different outcomes