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Table 1 Baseline clinical characteristics in patients with and without m-MCAI

From: 20-hydroxyeiscosatetraenoic acid may be as a predictor of malignant middle cerebral artery infarction in patients with massive middle cerebral artery infarction

Characteristics

Patients with m-MCAI

(n = 77)

Patients without m-MCAI

(n = 179)

P value

Age (years)

58.9 ± 14.2

66.7 ± 15.5

< 0.001

Men (n, %)

36 (46.8)

87 (48.6)

0.786

>60 y of age (n,%)

32 (41.6)

108 (60.3)

< 0.001

Hypertension (n, %)

35 (45.5)

94 (52.5)

0.301

Diabetes mellitus (n, %)

16 (20.8)

37 (20.7)

0.987

Atrial fibrillation (n, %)

45 (58.4)

66 (36.9)

0.002

Current smoker (n, %)

19 (24.7)

39 (21.8)

0.637

Dyslipidemia (n, %)

12 (15.6)

35 (19.6)

0.482

Plasma glucose (mmol/L)

7.7 ± 3.2

7.9 ± 3.5

0.652

Onset to admission time (h)

21.3 ± 8.9

23.2 ± 10.2

0.151

NIHSS score on admission

16.1 ± 7.3

14.9 ± 7.9

0.147

SBP on admission (mm Hg)

146.7 ± 26.4

144.7 ± 25.2

0.578

DBP on admission (mm Hg)

84.8 ± 14.7

85.3 ± 15.6

0.712

Temperature on admission, °C

36.9 ± 1.5

36.7 ± 1.7

0.349

Left MCA infarction (n, %)

49 (63.6)

78 (43.6)

0.004

Etiology (n, %)

  

0.014

 Large-artery atherosclerosis

16 (20.8)

43 (24.0)

 

 Cardioembolism

49 (63.6)

74 (41.3)

 

 Other determined etiology

2 (2.6)

12 (6.7)

 

 Undetermined etiology

10 (13.0)

50 (27.9)

 

Mechanical ventilation (n, %)

27 (35.1)

3 (1.7)

< 0.001

Decompressive craniectomy (n, %)

21 (27.2)

3 (1.7)

< 0.001

Outcome (n, %)

 Early neurological deterioration

77 (100.0)

47 (26.3)

< 0.001

 Mortality during 3 months

60 (77.9)

75 (41.9)

< 0.001

 mRS > 2 points at 3 months

74 (96.1)

128 (71.5)

< 0.001

  1. m-MCAI malignant middle cerebral artery infarction, MCA middle cerebral artery; NIHSS National Institutes of Health Stroke Scale, SBP systolic blood pressure, DBP diastolic blood pressure, tPA tissue plasminogen activator, mRS modified Rankin Scale