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Table 5 Associations for functional outcomes, duration of hospital stay and complications at 3 months post-thrombolysis

From: Outcomes of stroke patients undergoing thrombolysis in Sri Lanka; an observational prospective study from a low-middle income country

Variable

P value against each outcome

 

Independent mRS at 3 months

Favourable mRS at 3 months

Duration of hospital stay

Intracranial Haemorrhage at 3 months

Death at 3 months

History

     

Agea

NS

NS

NS

NS

NS

BMIa

NS

NS

NS

NS

< 0.001

Time to admissiona

0.012

0.026

NS

NS

NS

Time to reperfusiona

NS

0.009b

NS

NS

NS

Diabetes mellitus

NS

0.044

NS

NS

NS

Hypertension

NS

NS

NS

NS

NS

Previous ischaemic heart disease

NS

NS

NS

NS

NS

Atrial fibrillation

NS

NS

NS

NS

NS

Heart failure

NS

NS

NS

NS

NS

Previous stroke

NS

NS

NS

NS

NS

Smoking

NS

NS

NS

NS

NS

On aspirin

NS

NS

NS

NS

NS

On clopidogrel

NS

NS

NS

NS

NS

On statins

NS

NS

NS

NS

NS

Examination and investigations

     

Vascular territory of stroke

NS

NS

NS

NS

NS

On admission

NIHSSa

< 0.001b

0.001b

0.044

NS

NS

CT- ASPECT scorea

NS

NS

NS

NS

NS

CT – MCA hyperdense sign

NS

NS

NS

NS

0.040

CT - Leukoaraiosis

0.002

< 0.001b

NS

NS

NS

Glucosea

NS

NS

NS

NS

NS

SBP a

NS

0.04

NS

NS

NS

DBP a

NS

0.009

0.017

NS

NS

Platelet count

NS

NS

NS

NS

NS

INR < 1.7

NS

NS

NS

NS

NS

eGFR

NS

NS

NS

NS

NS

Haematocrit

NS

NS

0.019

NS

NS

Treatment

     

Low vs. high dose rTPA

0.031

NS

NS

NS

NS

  1. acontinuous variables – evaluated with independent T test, All other categorical variables were evaluated with chi square test, NS – non-significant, b associations that remained significant in the adjusted analysis, BMI body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, CT Computed tomography, rTPA recombinant tissue plasminogen inhibitor, NIHSS National Institutes of Health Stroke Score, mRS modified Rankin Scale, eGFR estimated glomerular filtration rate, MCA middle cerebral artery, INR international normalised ratio, ASPECTS Alberta Stroke Programme early CT score, NS Not significant