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Table 4 Diagnostic power of GWR (cutoff 1.17 for poor neurologic outcome) in different subgroups

From: Prognostication of neurologic outcome using gray-white-matter-ratio in comatose patients after cardiac arrest

Population Sensitivity Specificity ppv npv AUC
Neurologic outcome  
 All patients (n = 91) 50.7 (38.4–63.0) 100 (84.6–100) 100 39.3 (33.7–45.1) 0.754 (0.652–0.838)
Time interval admission to CT
 ≤12 h (n = 36) 17.4 (5.0–28.8) 100 (75.3–100) 100 40.6 (36.2–45.2) 0.587 (0.411–0.748)
 > 12 h (n = 55) 67.4 (52.0–80.5) 100 (66.4–100) 100 37.5 (28.4–47.6) 0.837 (0.713–0.923)
Targeted temperature management
 Mild hypothermia (n = 53) 59.5 (43.4–74.4) 100 (71.5–100) 100 39.3 (31.0–48.3) 0.798 (0.665–0.895)
 Normothermia (n = 38) 37.0 (19.4–57.6) 100 (71.5–100) 100 39.3 (32.6–46.4) 0.685 (0.524–0.826)
Mortality  
 All patients (n = 91) 51.7 (38.2–65.0) 84.8 (68.1–94.9) 85.7 (72.0–93.3) 50.0 (42.5–57.5) 0.683 (0.577–0.776)
Time interval admission to CT
 ≤12 h (n = 36) 15.8 (3.4–39.6) 94.1 (71.3–99.9) 75.0 (25.6–96.3) 50.0 (44.3–55.7) 0.550 (0.375–0.715)
 > 12 h (n = 55) 69.2 (52.4–83.0) 75.0 (47.6–92.7) 87.1 (73.8–94.2) 50.0 (36.6–63.4) 0.721 (0.584–0.834)
Targeted temperature management
 Mild hypothermia (n = 53) 60.0 (42.1–76.1) 77.8 (52.4–93.6) 84.0 (68.0–92.9) 50.0 (38.3–61.7) 0.689 (0.547–0.809)
 Normothermia (n = 38) 39.1 (19.7–61.5) 93.3 (68.1–99.8) 90.0 (55.9–98.5) 50.0 (41.2–58.8) 0.662 (0.491–0.807)
  1. Data are percentages and 95% confidence intervals. Ppv positive predictive value, npv negative predictive value, AUC area under the curve