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Table 4 Diagnostic power of GWR (cutoff 1.17 for poor neurologic outcome) in different subgroups

From: Prognostication of neurologic outcome using gray-white-matter-ratio in comatose patients after cardiac arrest

Population

Sensitivity

Specificity

ppv

npv

AUC

Neurologic outcome

 

 All patients (n = 91)

50.7 (38.4–63.0)

100 (84.6–100)

100

39.3 (33.7–45.1)

0.754 (0.652–0.838)

Time interval admission to CT

 ≤12 h (n = 36)

17.4 (5.0–28.8)

100 (75.3–100)

100

40.6 (36.2–45.2)

0.587 (0.411–0.748)

 > 12 h (n = 55)

67.4 (52.0–80.5)

100 (66.4–100)

100

37.5 (28.4–47.6)

0.837 (0.713–0.923)

Targeted temperature management

 Mild hypothermia (n = 53)

59.5 (43.4–74.4)

100 (71.5–100)

100

39.3 (31.0–48.3)

0.798 (0.665–0.895)

 Normothermia (n = 38)

37.0 (19.4–57.6)

100 (71.5–100)

100

39.3 (32.6–46.4)

0.685 (0.524–0.826)

Mortality

 

 All patients (n = 91)

51.7 (38.2–65.0)

84.8 (68.1–94.9)

85.7 (72.0–93.3)

50.0 (42.5–57.5)

0.683 (0.577–0.776)

Time interval admission to CT

 ≤12 h (n = 36)

15.8 (3.4–39.6)

94.1 (71.3–99.9)

75.0 (25.6–96.3)

50.0 (44.3–55.7)

0.550 (0.375–0.715)

 > 12 h (n = 55)

69.2 (52.4–83.0)

75.0 (47.6–92.7)

87.1 (73.8–94.2)

50.0 (36.6–63.4)

0.721 (0.584–0.834)

Targeted temperature management

 Mild hypothermia (n = 53)

60.0 (42.1–76.1)

77.8 (52.4–93.6)

84.0 (68.0–92.9)

50.0 (38.3–61.7)

0.689 (0.547–0.809)

 Normothermia (n = 38)

39.1 (19.7–61.5)

93.3 (68.1–99.8)

90.0 (55.9–98.5)

50.0 (41.2–58.8)

0.662 (0.491–0.807)

  1. Data are percentages and 95% confidence intervals. Ppv positive predictive value, npv negative predictive value, AUC area under the curve