Table 2 Characteristics of ICH patients within 24 h of ICH symptom onset (n = 436), stratified by HE
Characteristic | With HE (n = 115) | Without HE (n = 321) | p Value | OR (95% CI) |
|---|---|---|---|---|
Age, years | 63.0 (14.5) | 58.8 (13.7) | 0.007 | NA |
Male | 86 (74.8) | 206 (64.2) | 0.038 | 1.656 (1.026-2.672) |
GCS | 13 (9-15) | 14 (9-15) | 0.766 | NA |
NIHSS | 9 (3-14) | 8 (3-14) | 0.773 | NA |
BP on admission, mmHg | NA | |||
Systolic BP | 165.4 (27.5) | 166.6 (26.8) | 0.680 | |
Diastolic BP | 94.5 (18.1) | 96.3 (16.4) | 0.323 | |
Comorbidities | ||||
Hypertension | 76 (66.1) | 199 (62.0) | 0.435 | 1.195 (0.764-1.868) |
Diabetes mellitus | 13 (11.3) | 27 (8.4) | 0.356 | 1.388 (0.690-2.792) |
Dyslipidemia | 27 (23.5) | 93 (29.0) | 0.258 | 0.752 (0.459-1.233) |
Heart disease | 8 (7.0) | 20 (6.2) | 0.785 | 1.125 (0.481-2.630) |
Stroke history | 13 (11.3) | 31 (9.7) | 0.615 | 1.192 (0.601-2.367) |
Smoking | 39 (33.9) | 85 (26.5) | 0.129 | 1.425 (0.900-2.254) |
Alcohol consumption | 35 (30.4) | 90 (28.0) | 0.626 | 1.123 (0.705-1.789) |
HBV infection | 80 (69.6) | 222 (69.2) | 0.935 | 1.019 (0.642-1.619) |
Antiplatelet drugs | 4 (3.5) | 8 (2.5) | 0.579 | 1.410 (0.416-4.774) |
ICH volume, ml | NA | |||
At admission | 24.3 (8.3-45.4) | 13.0 (7.6-30.5) | 0.005 | |
At follow-up | 33.8 (16.5-56.2) | 13.2 (6.7-30.0) | <0.001 | |
Location of bleed | 0.001 | NA | ||
Deep location | 60 (52.2) | 227 (70.7) | ||
Lobar location | 37 (32.2) | 58 (18.1) | ||
Infratentorial location | 18 (15.7) | 36 (11.2) | ||
IVH | 29 (25.2) | 95 (29.6) | 0.372 | 0.902 (0.494-1.302) |
Symptom onset to first CT, h | 6.0 (3.5-10.5) | 7.0 (4.0-13.0) | 0.083 | NA |
Time between the first and second CT, h | 22.0 (4.0-32.0) | 23.0 (7.0-38.0) | 0.340 | NA |
Laboratory findings | NA | |||
Platelet count, ×109/L | 140 (112-202) | 160 (124-200) | 0.038 | |
International normalized ratio | 1.0 (0.9-1.0) | 1.0 (0.9-1.0) | 0.887 | |
Prothrombin time, sec | 11.4 (10.8-12.1) | 11.4 (10.9-12.0) | 0.788 | |
APTT, sec | 26.5 (24.3-29.3) | 26.5 (24.3-29.3) | 0.844 | |
Aspartate transaminase, IU/L | 25 (20-32) | 24 (20-31) | 0.652 | |
Alanine transaminase, IU/L | 20 (15-28) | 21 (15-32) | 0.518 | |
Albumin, g/dL | 43.3 (41.2-46.1) | 43.4 (41.1-43.4) | 0.835 | |
Liver fibrosis index | NA | |||
APRI | 0.4 (0.3-0.7) | 0.4 (0.3-0.6) | 0.245 | |
AARPRI | 1.3 (0.8-1.8) | 1.1 (0.8-1.6) | 0.069 | |
FIB 4 | 2.4 (1.6-3.9) | 2.1 (1.3-3.0) | 0.016 | |
mFIB 4 | 5.2 (3.4-8.5) | 4.4 (2.6-7.1) | 0.015 | |
FibroQ | 5.2 (3.4-8.1) | 4.3 (2.6-7.1) | 0.024 | |
Forns index | 6.6 (5.2-7.9) | 6.2 (4.9-7.3) | 0.017 | |