Table 1 Baseline characteristics by WBC quartiles of participants in the GBCS, 2003–2017 (n = 27,811)
Characteristics | Quartiles of WBC (*10^9/L) | P value trend | |||
|---|---|---|---|---|---|
1st (< 5.3) | 2nd (5.3–6.1) | 3rd (6.2–7.2) | 4th (> 7.2) | ||
Number, n | 6946 | 6912 | 7093 | 6860 | Â |
Sex, male(%) | 1468 (21.1) | 1767 (25.6) | 2004 (28.3) | 2392 (34.9) | < 0.001 |
Age (years) | 61.1 ± 7.1 | 61.8 ± 7.2 | 62.3 ± 7.0 | 62.9 ± 7.0 | < 0.001 |
Education (%) |  |  |  |  | < 0.001 |
 Primary or below | 2536 (36.5) | 2861 (41.4) | 3177 (44.8) | 3406 (49.7) |  |
 Middle school | 3685 (53.1) | 3405 (49.3) | 3352 (47.3) | 2932 (42.7) |  |
 College or above | 725 (10.4) | 646 (9.3) | 564 (8.0) | 522 (7.6) |  |
Occupation |  |  |  |  | < 0.001 |
 Manual | 3277 (47.2) | 3346 (48.4) | 3551 (50.1) | 3565 (52.0) |  |
 Non-manual | 2267 (32.6) | 2262 (32.7) | 2294 (32.3) | 2130 (31.0) |  |
 Others | 1402 (22.2) | 1304 (18.9) | 1248 (17.6) | 1165 (17.0) |  |
Smoking, n (%) |  |  |  |  | < 0.001 |
 Never | 6086 (87.6) | 5822 (84.2) | 5708 (80.5) | 4909 (71.6) |  |
 Former | 530 (7.6) | 596 (8.6) | 682 (9.6) | 714 (10.4) |  |
 Current | 330 (4.8) | 494 (7.2) | 703 (9.9) | 1237 (18.0) |  |
Alcohol drinking, n (%) |  |  |  |  | < 0.001 |
 Never | 5016 (72.2) | 4835 (70.0) | 4965 (70.0) | 4725 (68.9) |  |
 Former | 119 (1.7) | 150 (2.2) | 169 (2.4) | 203 (3.0) |  |
 Current | 1811 (26.1) | 1927 (27.8) | 1959 (27.6) | 1932 (28.1) |  |
Physical activity, IPAQ, n (%) |  |  |  |  | < 0.001 |
 Inactive | 649 (9.3) | 505 (7.3) | 560 (7.9) | 541 (7.9) |  |
 Moderate active | 2844 (41.0) | 2771 (40.1) | 2855 (40.2) | 2876 (41.9) |  |
 Active | 3453 (49.7) | 3636 (52.6) | 3678 (51.9) | 3443 (50.2) |  |
Body mass index, kg/m2 |  |  |  |  | < 0.001 |
  < 18.5 | 562 (8.1) | 295 (4.3) | 199 (2.8) | 190 (2.8) |  |
 18.5–23.9 | 4119 (59.3) | 3608 (52.2) | 3339 (47.1) | 2882 (42.0) |  |
 24–27.9 | 1909 (27.5) | 2429 (35.1) | 2734 (38.5) | 2785 (40.6) |  |
  ≥ 28 | 356 (5.1) | 580 (8.4) | 821 (11.6) | 1003 (14.6) |  |
Self-rated health, n (%) (good/very good) | 5724 (82.4) | 5793 (83.8) | 5899 (83.2) | 5561 (81.1) | < 0.001 |
 Hypertension, n (%) | 1462 (21.0) | 1748 (25.3) | 2189 (30.9) | 2417 (35.2) | < 0.001 |
 Diabetes, n (%) | 522 (7.5) | 751 (10.9) | 997 (14.1) | 1359 (19.8) | < 0.001 |
 Dyslipidemia, n (%) | 5517 (79.4) | 5694 (82.4) | 5985 (84.4) | 5828 (85.0) | < 0.001 |
 Cancer, n (%) | 180 (2.6) | 137 (2.0) | 122 (1.7) | 100 (1.5) | < 0.001 |
 GU disease, n (%) | 2035 (29.3) | 1873 (27.1) | 1853 (26.1) | 1644 (24.0) | < 0.001 |
 Chest disease, n (%) | 1060 (15.3) | 1076 (15.6) | 1039 (14.6) | 1038 (15.1) | 0.50 |
 NEUT, *10^9/L | 2.6 ± 0.76 | 3.3 ± 0.47 | 4.0 ± 0.95 | 5.4 ± 1.24 | < 0.001 |
 LYM, *10^9/L | 1.7 ± 0.36 | 2.0 ± 0.41 | 2.2 ± 0.48 | 2.6 ± 0.67 | < 0.001 |
 Platelet, *10^9/L | 203.6 ± 51.3 | 221.6 ± 57.7 | 233.9 ± 55.7 | 250.4 ± 65.8 | < 0.001 |
 CRP, mg/L | 2.8 ± 2.4 | 3.1 ± 2.5 | 3.6 ± 2.8 | 4.2 ± 3.2 | < 0.001 |
 No. of all stroke deaths | 89 (0.013) | 98 (0.014) | 136 (0.019) | 180 (0.026) | < 0.001 |
 No. of ischaemic stroke | 42 (0.0060) | 39 (0.0056) | 66 (0.0093) | 80 (0.012) | < 0.001 |
 No. of haemorrhagic stroke | 32 (0.0046) | 37 (0.0054) | 42 (0.0059) | 63 (0.0092) | < 0.001 |