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Table 2 Biomarker values at three-month follow-up by ischemic stroke subtype at baseline1

From: Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke

  Atherosclerosis (N = 26) Cardioembolic (N = 62) CSVD
(N = 75)
Unknown
(N = 141)
P-value
CRP2, mean (SD) 1.93 (3.29) 3.06 (3.78) 1.88 (2.56) 1.58 (3.71) 0.032
IL-6, mean (SD) 3.71 (1.95) 5.70 (2.18) 3.97 (2.18) 4.26 (2.39) 0.038
Neopterin, mean (SD) 16.0 (1.5) 20.3 (1.7) 16.0 (1.4) 16.0 (1.5) 0.003
PAr, mean (SD) 0.66 (1.77) 0.73 (1.73) 0.60 (1.73) 0.60 (1.56) 0.087
KA, mean (SD) 59.7 (1.5) 67.4 (1.4) 59.7 (1.5) 57.4 (1.5) 0.093
  1. 1The category “other determined” was excluded because of low sample size. The analyses were conducted on log-transformed variables, and the values were transformed back after analysis
  2. 2For CRP: Atherosclerosis: N = 20, cardioembolic: N = 46, CSVD: N = 50, Unknown: N = 100. CSVD=cerebral small vessel disease. CRP = C-reactive protein IL-6 = Interleukin-6. PAr = pyridoxic acid ratio-index = 4-pyridoxic acid:(pyridoxal+pyridoxal 5′-phosphate). KA = kynurenic acid. The analyses were done using a one-way ANOVA